The Unmapped Mind: A Memoir of Neurology, Incurable Disease and Learning How to Live

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Aug 162018
 

“My daughter took her first steps on the day I was diagnosed – a juxtaposition so perfect, so trite, so filled with the tacky artifice of real life that I am generally too embarrassed to tell anybody about it.”

Shortly after his daughter Leontine was born, Christian Donlan’s world shifted an inch to the left. He started to miss light switches and door handles when reachingfor them. He would injure himself in a hundred stupid ways every day. First playful and then maddening, these strange experiences were the early symptoms of multiple sclerosis, an incurable and degenerative neurological disease.

Ashis young daughter starts to investigate the world around her, he too finds himself exploring a new landscape – the shifting and bewildering territory ofthe brain. He is a tourist in his own body, a stranger in a place that plays bizarre tricks on him, from dizzying double vision to mystifying memory loss. Determined to master his new environment, Christian takes us on a fascinating and illuminating journey: through the history of neurology, the joys andanxieties of parenthood, and the ultimate realisation of what, after everything you take for granted has been stripped away from you, is truly important in life.

An Unmapped Mind is a profoundly personal, uplifting and enriching memoir that will change the way you see your body, your mind, and the world around you.

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Sleep Disorders in Neurology: A Practical Approach, 2nd edition

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Aug 152018
 

The acclaimed guide to quickly and confidently diagnosing and treating sleep disorders in neurological disease now with more algorithms and tables

The diagnosis and treatment of sleep disorders can be extremely challenging for physicians, especially when there is underlying neurological disease. In addition to the primary sleep disorders, there is a growing clinical interest in sleep disturbances associated with common neurological disorders such as Parkinson′s disease. This updated and expanded edition of the critically acclaimed Sleep Disorders in Neurology: A Practical Approach provides doctors with expert recommendations and clear guidance on identifying sleep disorders in patients suffering from neurological diseases and providing effective treatment plans.

In creating this Second Edition doctors Overeem and Reading made every effort to further enhance the practical approach of the first edition by adding additional algorithms and tables to assist physicians in more rapid decision making. In addition, they expanded the content to include greater coverage of primary sleep disorders. Classification and diagnosis chapters have been revamped to follow the 3rd International Classification of Sleep Disorders.

Offers physicians, with a practical approach to diagnosing and treating complex sleep disorders
Draws on the expertise of neurologists who specialize in the disorders under discussion
Features quick–access algorithms that help physicians rapidly diagnose and treat primary and secondary sleep disorders with confidence
Provides guidance on when to consult a sleep specialist in managing a particular sleep disorder and
Written by a multinational author team who provide a wider perspective and range of clinical experience
Sleep Disorders in Neurology: A Practical Approach, Second Edition is an essential resource for sleep medicine specialists, as well as clinicians and health care professionals not specifically trained in sleep medicine, but who nevertheless need to manage neurologically damaged patients with increasingly recognized sleep/wake disturbances.

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Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and Its Treatment

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Aug 152018
 

Neuro-oncology has evolved substantially as a clinical and research discipline over the past few decades. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition provides clinicians from various backgrounds and levels of training with a reference to help focus the differential diagnosis, treatment strategy, and management plan for the cancer patient with neurologic symptoms and findings. The volume begins with an overview of the field of neuro-oncology and a review of the role of neuroimaging in the diagnosis of neuro-oncologic disease. Several chapters on interpretation and management of common neuro-oncologic symptoms follow. Subsequent sections contain chapters on the direct and indirect neurologic complications of cancer as well as complications of therapy. The final section focuses on the spectrum and management of neurologic disease in patients with cancer of specific organs. Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment, Second Edition is an important new work that aims to broaden and deepen the familiarity of clinicians with the range and management of neuro-oncologic diseases in order to improve the quality of care for cancer patients.
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Pediatric Neurology (What Do I Do Now?)

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Aug 142018
 

What do I do now? Pediatric patients with neurological symptoms or problems pose many clinical challenges and even experienced clinicians occasionally arrive at the point where diagnostic, work-up, treatment, or prognostic thinking becomes blocked. From time to time, children are brought into the pediatrician’s office with puzzling neurological symptoms—breath holding spells, refusal to walk, infantile spasms, skin lesions, floppy or absent reflexes—that leave their doctors wondering “what do I do now?” Pediatric Neurology serves the need for a quick reference tool to address these perplexing pediatric neurological symptoms and disorders. Dr. Gregory L. Holmes, Department Chair and Professor of Pediatrics and Neurology at Dartmouth Medical School, presents 28 representative cases of both common and rare pediatric neurological problems and diseases including but not limited to: Dopamine Responsive Dystonia, Fragile X Syndrome, Hashimoto’s Encephalopathy and Rett Syndrome. The bedside consultation presentation of the cases encourages the reader, whether she or he be a pediatrician, primary care practitioner or medical student, to formulate a differential diagnosis and treatment plan for a wide variety of pediatric neurological problems and diseases.
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Behavioural Neurology of Antiepileptic Drugs : A Practical Guide

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Aug 132018
 


Antiepileptic drugs are among the most commonly prescribed medications by both neurologists and psychiatrists, as they exert a number of effects which extend far beyond their anticonvulsant properties. There is growing evidence that each antiepileptic drug is characterised by a specific behavioural profile. Behavioural Neurology of Antiepileptic Drugs: A Practical Guide offers a user-friendly guide to the use of antiepileptic drugs and their behavioural effects on patients with epilepsy and primary psychiatric conditions.

Written over 18 chapters, this practical handbook guides the reader through the breadth of medications used in modern epilepsy and psychiatry practice alphabetically, including information on each drug’s indications, contra-indications, side-effects, and important interactions. This resource covers practical information on prescribing and monitoring to ensure the reader has the most up-to-date evidence-based guidance at their fingertips, and diagrams are used throughout to aid visual learning.

With up-to-date content and a practical approach, Behavioural Neurology of Antiepileptic Drugs: A Practical Guide is an invaluable resource for consultants and trainees in neurology, psychiatry, and neuropsychiatry, as well as to pharmacists and specialist epilepsy nurses.

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The Epilepsy Prescriber’s Guide to Antiepileptic Drugs – Cambridge University Press; 3rd Edition (August 2018 Release)

 Neurology/Neurosurgery  Comments Off on The Epilepsy Prescriber’s Guide to Antiepileptic Drugs – Cambridge University Press; 3rd Edition (August 2018 Release)
Aug 102018
 

This essential and concise clinical reference guide serves diverse clinicians and allied health professionals who prescribe antiepileptic drugs in contemporary clinical practice. Fully updated, it features chapters on newly-approved drug brivaracetam, updated paediatric prescribing, use in particular populations including women, the elderly, and patients with cognitive impairment, as well as sections on teratogenicity, pregnancy, and lactation. In full colour throughout, the guide provides comprehensive antiepileptic drug (AED) prescribing information, covering all thirty-five AEDs in alphabetical order. Each chapter features eight coloured sections including general therapeutics, pharmacokinetics, interaction profile, adverse effects, dosing and use, special population considerations, a summary overview, and suggested reading. Perfect for quick reference use, the guide is practical and essential for all AED drug prescribers including adult and paediatric neurologists, neurosurgeons, psychiatrists, internists, geriatricians, paediatricians, family physicians, as well as allied health professionals and resident, fellow, and student trainees in all related medical fields.

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Handbook of Stress Medicine and Health

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Aug 082018
 

Research now shows us that long-term activation of the stress cycle can have a hazardous, even lethal, effect on the body, increasing the risk of obesity, heart disease, depression, cancer, and other illnesses. This new edition of an award-winning book presents cutting-edge research on the effects of stress.
Edited by one of the world’s authorities in stress management, occupational psychology, and occupational medicine, Handbook of Stress Medicine and Health, Second Edition offers a completely revised and updated look at the different types of stress, including their characteristics, symptoms, duration, and treatment approaches. The text proposes a generic theory on stress and health and explores the relationship of stress to a variety of health outcomes, including heart disease, cancer, mental health, burnout, and complications of the endocrine and immune systems. It addresses the link between stress and personality, and discusses the impact of social support on various health conditions. The final chapters deal with stress and its consequences, such as the emotional processing of traumatic events, dealing with stress in families and in chronic disease, and coping with stress in the workplace.
With contributions from the foremost leaders in the field, this authoritative book evaluates a wide range of psychosocial factors that contribute to many of today’s major illnesses. It also proposes strategies for prevention and management, which will hopefully encourage future research into the reduction of stress.

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Textbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function

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Aug 072018
 

This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity.
The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease.
This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.

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Neurodevelopmental Disorders: Research challenges and solutions

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Aug 062018
 

Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.
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Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting

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Aug 062018
 

 

In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum–or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author’s website, www.izhikevich.com.

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