Functional Neuroimaging with Multiple Modalities

 Neurology/Neurosurgery, Radiology  Comments Off on Functional Neuroimaging with Multiple Modalities
Feb 112018


Searching for an objective and specific in vivo biomarker for normal physiology and early disease diagnosis has always been a major goal, but also one of the most challenging aspects in brain research. Possible earlier identification of the key pathological signature of diseases (for instance, Alzheimer’s disease (AD)) is critical for efficient treatment and disease prevention. The concept of combined imaging features is based on the recent accumulating evidence that neither PET nor MRI alone is enough for characterizing the earliest AD pathology. The results of this book will, for the first time, highlight in vivo the possibility to describe the early detection and multiple biomarkers based on combined imaging features using PET-MRI, which is the most ideal model for such studies. The newly-developed hybrid imaging technology combining PET and MRI (PET/MRI) for the past few years is emerging, and has drawn much attention in technical developments and clinical applications. PET-MRI opens new horizons in multi-parametric neuroimaging for clinical research that allows simultaneous imaging of multiple parametric changes, such as blood flow and metabolism at the same time. This integration significantly decreases the potential errors in image registration, the difficulty of interpreting underlying coexisting pathophysiological events, and most importantly, patient discomfort.
This book will provide the most up-to-date and current status of multiple neuroimaging techniques. The most intriguing application of multi-modality neuroimaging lies in simultaneous interpretation and unique information that each modality can offer. Therefore, this book will present some forefront and interesting examples for the first time in this field of research. This will hopefully trigger the interest of colleagues in this challenging field and help facilitate the applications of the neuroimaging techniques described.



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The Neurobiological Basis of Memory: A System, Attribute, and Process Analysis

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Feb 112018


This exciting volume offers an up-to-date tour of current trends in the neurobiology of memory while saluting Raymond Kesner’s pioneering contributions to the field as a theorist and researcher, teacher and mentor. Starting with his signature chapter introducing the Attribute Model of Memory, the first half of the book focuses on the central role of the hippocampus in processing dimensions of space and time, and branches out to memory system interactions across brain structures. Later chapters apply the attribute model to multiple functions of memory in learning, and to specific neurological contexts, including Huntington’s disease, traumatic brain injury, and Fragile X. As a bonus, the book concludes with an essay on Kesner’s life and work, and reminiscences by colleagues.



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Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity 1st Edition

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Feb 112018


The clinical approaches to the chronic degenerative diseases that drain our resources, and compromise our well-being, have become almost exclusively symptom-focused. The common wisdom is that they are idiopathic with final outcomes to be managed rather than prevented or cured. That they are potentially reversible rarely enters any discussion between doctor and patient. Reversibility of Chronic Disease and Hypersensitivity, Volume 5: Treatment Options of Chemical Sensitivity, the final volume of this set, offers a much different perspective on chronic degenerative disease; one that disputes the idiopathic label attached to most, as well as the usual fatalistic prognosis.



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A User’s Guide to the Brain: Perception, Attention, and the Four Theatres of the Brain

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Feb 102018


John Ratey, bestselling author and clinical professor of psychiatry at Harvard Medical School, lucidly explains the human brain’s workings, and paves the way for a better understanding of how the brain affects who we are. Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior.

By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.

In A User’s Guide to the Brain, Ratey clearly and succinctly surveys what scientists now know about the brain and how we use it. He looks at the brain as a malleable organ capable of improvement and change, like any muscle, and examines the way specific motor functions might be applied to overcome neural disorders ranging from everyday shyness to autism. Drawing on examples from his practice and from everyday life, Ratey illustrates that the most important lesson we can learn about our brains is how to use them to their maximum potential.


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Neurobiology: A Functional Approach

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Feb 102018

Focusing on the problems that brains help organisms solve, Neurobiology: A Functional Approach asks not only how the nervous system works but also why it works as it does. This text introduces readers to neurobiology through an evolutionary, organismal, and experimental perspective. With a strong emphasis on neural circuits and systems, it bridges the gap between the cellular and molecular end and the cognitive end of the neuroscience spectrum, allowing students to grasp the full breadth of the subject. Neurobiology covers not only what neuroscientists have learned about the brain in terms of facts and ideas, but also how they have learned it through key experiments.
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Neurology Image-Based Clinical Review

 Neurology/Neurosurgery, Radiology  Comments Off on Neurology Image-Based Clinical Review
Feb 102018

Neuroimaging has become an integral part of clinical neurology practice in tandem with good history taking and physical examination. This is the first all-in-one guide, presenting illustrative examples of signature neuroimaging findings in clinical context specifically for neurologists. With more than 1,500 images, the authors have assembled an accessible resource and review that presents over 170 core topics using the imaging findings as a platform to discuss pathophysiology, clinical presentation, and disease management. Written with the practitioner or student of neurology in mind, Neurology Image-Based Clinical Review profiles each condition in an easy-to-read format, alongside a wealth of images designed to help develop proficiency in recognizing and treating both common and rare neurologic conditions.

This unique book is organized into fifteen chapters covering all major areas of neurology including stroke, hemorrhage, neoplasms, epilepsy, trauma, neurodegenerative conditions, infectious diseases, pediatric syndromes, and much more. Each topic is introduced with a brief case scenario and image-based diagnosis, followed by bulleted introduction, clinical presentation, radiographic appearance and diagnostic hallmarks, differential diagnosis, and treatment. Numerous examples throughout foster familiarity with key imaging findings and boost confidence interpreting MRI, CT, MRA, angiography, EEG, gross, and microscopic neuropathology images. Selected references for further study follow each topic.

Neurology Image-Based Clinical Review is an essential reference for practicing neurologists, students, and residents looking to hone their knowledge, or anyone sharpening clinical and interpretive skills for board or MOC review.

Key Features:

Comes with free access to the fully-searchable downloadable e-book, including an image bank
Covers the full spectrum of neurologic disease with over 170 topics and more than 1,500 images
Includes chapters on commonly encountered problems and rare syndromes that may be missed in the clinic
Presents the latest information on clinical presentation, diagnosis, treatment, and differential diagnoses of various neurological disorders
Consistent format for easy readability and targeted review



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Principles and Practice of Keyhole Brain Surgery

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Feb 082018

Developed 20 years ago by leading innovators in the
field, the keyhole concept of brain surgery has become an integral part of the
practice of neurosurgery. This timely and comprehensive book covers the
thinking, philosophy, and techniques of modern keyhole brain surgery, including
a realistic assessment of its benefits and limitations. Written by expert
practitioners and highlighted by vivid surgical illustrations and procedural
videos, Principles and Practice of Keyhole Brain Surgery

functions as an
experienced mentor working side by side with neurosurgeons as they master the

Special Features:

Introduces the basic principles of
the keyhole approach, including the practical, technical, and logistical
aspects of planning procedures and operating through small openings

Beautifully illustrated with nearly 900 endoscopic images, diagrams, surgical
drawings, and operative photographs, many showing step-by-step
Details the pivotal role of the endoscope in keyhole brain
surgery and its ability to provide multiple angles of visualization,
including a useful catalog of clinical situations where the endoscope has
proven most effective
Demonstrates contemporary keyhole
approaches (e.g. the eyebrow/sub-frontal approach) in procedures for
supratentorial intra-axial brain tumors, tumors of the cribriform plate and
orbit, parasellar masses, craniopharyngiomas, tumors of the middle fossa
and cavernous sinus and many other conditions in the cranial
Offers more than 100 procedural videos on the Thieme’s
MediaCenter, narrated by the authors and aligned to chapters in the
book for an unparalleled learning resource
Providing all the information necessary to achieve
surgical goals through well placed, smaller openings—with the added benefits of
shorter procedures, fewer wound complications and better patient
outcomes—Principles and Practice of Keyhole Brain Surgery is essential for every neurosurgeon in practice today.


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Neural Computation, Neural Devices, and Neural Prosthesis

 Neurology/Neurosurgery  Comments Off on Neural Computation, Neural Devices, and Neural Prosthesis
Feb 062018


In the past decades, interdisciplinary investigations overlapping biology, medicine, information science, and engineering have formed a very exciting and active field that attracts scientists, medical doctors, and engineers with knowledge in different domains. A few examples of such investigations include neural prosthetic implants that aim to improve the quality of life for patients suffering from neurologic disease and injury; brain machine interfaces that sense, analyze, and translate electrical signals from the brain to build closed-loop, biofeedback systems; and fundamental studies of intelligence, cognitive functions, and psychological behaviors correlated to their neurological basis. Although this interdisciplinary area is still in its infancy, it can potentially create some of the most significant impact: treating diseases that are considered untreatable, interpretation and communication of neuron ensembles, or even a revolutionary perception and understanding of life different from philosophical or immaterial approaches. Fortunately, several academic societies recognize the value and impact of this growing field, firmly supporting related research. Such support will drive a booming future in the next twenty or thirty years. Research in this area is frequently project-driven, and the generated knowledge has been scattered in different fields of neuroscience, computation, material and technology, circuits and system, clinical reports, and psychology—the scope considerably across the boundary of traditionally defined disciplines. Neural Computation, Neural Devices, and Neural Prosthesis is intended to assemble such knowledge, from there suggesting a systematic approach guiding future educational and research activities. The targeted audience includes both students and researchers.
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Wyllie’s Treatment of Epilepsy: Principles and Practice (6th edition)

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Feb 052018


Helps you meet the challenges of epilepsy treatment with today’s best knowledge! Wyllie’s Treatment of Epilepsy: Principles and Practice, 6th edition, provides a broad, detailed, and cohesive overview of seizure disorders and contemporary treatment options. Written by the most influential experts in the field and thoroughly updated to provide the most current content, Wyllie’s Treatment of Epilepsy assists neurologists and epilepsy specialists, neurology residents and fellows, and neuropsychologists in assessing and treating their patients with the latest treatment options. Dr. Wyllie is once again joined by associate editors Dr. Barry Gidal and Dr. Howard Goodkin, as well as newcomers Dr. Joseph Sirven of the Mayo Clinic and Dr. Tobias Loddenkemper of Harvard Medical School. This book features: in-depth review of the subspecialties of epileptology, i.e., neuroimaging, epilepsy surgery, antiepileptic medications; offers a comprehensive single-volume text on epileptology; it is clinically oriented, evidence-based reference; and includes an online bank of over 500 board review-style questions highlighting key concepts for board examinations and clinical practice.




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A Sociological Approach to Acquired Brain Injury and Identity

 Neurology/Neurosurgery  Comments Off on A Sociological Approach to Acquired Brain Injury and Identity
Feb 032018


Inspired by the author’s personal experience of sustaining acquired brain injury (ABI), this path-breaking book explores the (re)construction of identity after ABI. It offers a way of understanding ABI through a social scientific lens, promoting an understanding that is generated through close engagement with the lives and experiences of ABI survivors.

The author follows the everyday experiences of six male survivors and critically investigates their identity (re)construction after their ABI. As well as demonstrating identity (re)construction after ABI, the experiences of the participants allow the reader to investigate neurological rehabilitation from their perspective. This book suggests that rehabilitation after ABI is often a continual process that extends beyond the formal, medically prescribed period. It also shows that identity after ABI is often (re)constructed in an unpredictable way; a way that emphasises the importance of reciprocal support and the uncertainty of future life.

A Sociological Approach to Acquired Brain Injury and Identity is essential reading for academics and students from a range of social scientific disciplines with an interest in biographical or ethnographic research methods. This book offers a social scientific view of rehabilitation and as such is also essential reading for academics, students and professionals with an interest in health and illness, particularly neurological rehabilitation and brain injury rehabilitation.




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