Vitamin D in Chronic Kidney Disease

 Nephrology  Comments Off on Vitamin D in Chronic Kidney Disease
Mar 282018
 

Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.
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Arterial Blood Gas Interpretation

 Critical Care, Internal Medicine, Nephrology, Respiratory Medicine  Comments Off on Arterial Blood Gas Interpretation
Feb 232018
 

This helpful, practical book begins with a clear explanation of acid-base balance, followed by a straightforward six-step approach to arterial blood gas interpretation. The authors then apply this approach to a wide range of realistic case studies that resemble situations readers are likely to encounter in practice.

With a strong focus on patient care pathways and including the most up-to-date information on arterial blood gas interpretation, this book will be invaluable to nurses, junior doctors and biomedical scientists as well as students and trainees in all these areas.

Contents include:

Introduction to acid-base balance
A systematic approach to ABG interpretation
Respiratory acidosis
Respiratory alkalosis
Metabolic acidosis
Metabolic alkalosis
Compensatory mechanisms
ABG analysis practice questions and answers

 

 

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Integration of Omics Approaches and Systems Biology for Clinical Applications

 Nephrology  Comments Off on Integration of Omics Approaches and Systems Biology for Clinical Applications
Jan 282018
 

 

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications

This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed.

Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting.

Describes a range of state of the art omics analytical platforms
Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis
Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer)
Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.

 

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http://nitroflare.com/view/91F3185BEE45366/1119183952_9781119183952.pdf

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Urine Proteomics in Kidney Disease Biomarker Discovery

 Nephrology  Comments Off on Urine Proteomics in Kidney Disease Biomarker Discovery
Jan 062018
 

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A Practical Manual of Renal Medicine: Nephrology, Dialysis and Transplantation

 Nephrology  Comments Off on A Practical Manual of Renal Medicine: Nephrology, Dialysis and Transplantation
Dec 222017
 

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http://nitroflare.com/view/13C7368CF70B92C/9812838716.pdf

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The Essentials of Clinical Dialysis 1st ed. 2018 Edition

 Nephrology  Comments Off on The Essentials of Clinical Dialysis 1st ed. 2018 Edition
Dec 082017
 

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Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals

 Nephrology  Comments Off on Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
Dec 042017
 

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Managing Segmental Renal Diseases

 Nephrology  Comments Off on Managing Segmental Renal Diseases
Nov 302017
 

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http://nitroflare.com/view/5D244B9514153FA/3319497200.pdf

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Genitourinary Radiology: Kidney, Bladder and Urethra: The Pathologic Basis

 Nephrology, Radiology  Comments Off on Genitourinary Radiology: Kidney, Bladder and Urethra: The Pathologic Basis
Nov 192017
 

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http://nitroflare.com/view/EECA734A9E23FCF/1848002440.pdf

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Resistant Hypertension in Chronic Kidney Disease

 Nephrology  Comments Off on Resistant Hypertension in Chronic Kidney Disease
Nov 142017
 

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http://nitroflare.com/view/3F5CA9DB4004366/3319568256.epub

http://nitroflare.com/view/EA8C63131516039/3319568256.pdf

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