Molecular and Therapeutic actions of Thymoquinone: Actions of Thymoquinone

 Miscellaneous  Comments Off on Molecular and Therapeutic actions of Thymoquinone: Actions of Thymoquinone
May 012018
 

Throughout history black seeds, Nigella sativa seeds, have been highly revered for its medicinal properties. Thymoquinone (TQ), an active principle component of the volatile oil of black cumin seeds, is an emerging natural compound with a wide range of medical applications, and has several beneficial pharmacological actions i.e anti-oxidant, anti-diabetic, anti-inflammatory, anti-microbial, anti-tumor, anti-mutagenic, anti-epileptic, hepatoprotective, neuroprotective, and nephroprotective. As such, it is important to move TQ from the bench to bedside. This book illustrates the therapeutic importance of TQ, offering a detailed account of some of its molecular and therapeutic properties, and discussing in depth its anti-diabetic, anti-cancer, anti-oxidant, anti-inflammatory, anti-microbial, anti-epileptic and hepatoprotective actions. Lastly, the book examines the future prospects of TQ research and its use as a pharmaceutical.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Health Economics and Healthcare Reform : Breakthroughs in Research and Practice

 Miscellaneous  Comments Off on Health Economics and Healthcare Reform : Breakthroughs in Research and Practice
Apr 302018
 

The effective delivery of healthcare services is vital to the general welfare and well-being of a country’s citizens. Financial infrastructure and policy reform can play a significant role in optimizing existing healthcare programs.

Health Economics and Healthcare Reform: Breakthroughs in Research and Practice is a comprehensive source of academic material on the importance of economic structures and policy reform initiatives in modern healthcare systems. Highlighting a range of pertinent topics such as clinical costing, patient engagement, and e-health, this book is ideally designed for medical practitioners, researchers, professionals, and students interested in the optimization of healthcare delivery.

Information Resources Management Association (IRMA) is a research-based professional organization dedicated to advancing the concepts and practices of information resources management in modern organizations. IRMA’s primary purpose is to promote the understanding, development and practice of managing information resources as key enterprise assets among IRM/IT professionals. IRMA brings together researchers, practitioners, academicians, and policy makers in information technology management from over 50 countries.

GET IT FREE HERE

http://nitroflare.com/view/06D46AA94F868DF/Health_Economics.pdf

ALTERNATIVE LINK

https://filejoker.net/jvzsxpy6b6qo

Share Button

m-Health : Fundamentals and Applications

 Miscellaneous  Comments Off on m-Health : Fundamentals and Applications
Apr 302018
 

Addresses recent advances from both the clinical and technological perspectives to provide a comprehensive presentation of m-Health

This book introduces the concept of m-Health, first coined by Robert S. H. Istepanian in 2003. The evolution of m-Health since then—how it was transformed from an academic concept to a global healthcare technology phenomenon—is discussed. Afterwards the authors describe in detail the basics of the three enabling scientific technological elements of m-Health (sensors, computing, and communications), and how each of these key ingredients has evolved and matured over the last decade. The book concludes with detailed discussion of the future of m-Health and presents future directions to potentially shape and transform healthcare services in the coming decades. In addition, this book:

– Discusses the rapid evolution of m-Health in parallel with the maturing process of its enabling technologies, from bio-wearable sensors to the wireless and mobile communication technologies from IOT to 5G systems and beyond
– Includes clinical examples and current studies, particularly in acute and chronic disease management, to illustrate some of the relevant medical aspects and clinical applications of m-Health
– Describes current m-Health ecosystems and business models
– Covers successful applications and deployment examples of m-Health in various global health settings, particularly in developing countries

GET IT FREE HERE

http://nitroflare.com/view/D9ED11100C63E15/m-Health.epub

ALTERNATIVE LINK

https://filejoker.net/jj03mfchqww6

Share Button

Targeting Trafficking in Drug Development

 Miscellaneous  Comments Off on Targeting Trafficking in Drug Development
Apr 302018
 

Cellular trafficking is only recently identified as a site for therapeutic intervention. This book provides up to date information on the mechanism for exploiting this area for drug development as well as a clear understanding of the individual components of cellular trafficking. The authors are experts in their areas and the book features tables and figures that enable comparison and clear understanding.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Peptide and Protein Interaction with Membrane Systems: Applications to Antimicrobial Therapy and Protein Drug Delivery

 Miscellaneous  Comments Off on Peptide and Protein Interaction with Membrane Systems: Applications to Antimicrobial Therapy and Protein Drug Delivery
Apr 282018
 

In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria. Bobone shows that AMPs interact with liposomes and she clarifies the structure of pores formed by one of these molecules. These results help us to understand how AMPs are selective for bacterial membranes and how their activity can be finely tuned by modifying their sequence. Findings which solve several conundrums debated in the literature for years. In addition, Bobone uses liposomes as nanotemplates for the photopolymerization of hydrogels – exploiting the self- assembly properties of phospholipids. Bobone was able to trap an enzyme using nanometeric particles, while still allowing its activity by the diffusion of substrates and products through the network of the polymer. The innovative nano devices described in this thesis could solve many of the hurdles still hampering the therapeutic application of protein-based drugs.

GET IT FREE HERE

http://nitroflare.com/view/4045FDAA8CCE90F/Peptide_and_Protein_Interaction_with_Membrane_Systems_Appli.pdf

ALTERNATIVE LINK

https://filejoker.net/yvnbyv2upw0j

Share Button

Management of Abdominal Hernias, Fifth Edition

 Miscellaneous  Comments Off on Management of Abdominal Hernias, Fifth Edition
Apr 262018
 

The fifth edition of this well-received book contains all the latest information on surgical techniques in abdominal hernia surgery and has been updated to reflect progress in robotic hernia surgery and minimally invasive approaches, as well as new materials used such as fully resorbable synthetic meshes. With chapters on management of complications and laparoscopic repair, among others, the book also contains newly-added accounts of the Milos technique, laparoscopic primary closure of defects and mesh.
For each of the surgical techniques described the reader will find information on pre- and post-operative management, instructions on theatre set-up and patient positioning, an account of the incision and access, as well as detailed operative steps and closure, and finally tips and pitfalls. From financial aspects to operative techniques and materials, this book provides a very comprehensive account of abdominal hernia management.

Richly illustrated to demonstrate the surgical procedures in detail this book is written by a team of world leaders in herniology. This is an indispensable guide to herniologists and hernia surgeons, worldwide.

GET IT FREE HERE

http://nitroflare.com/view/5BC9812A9DCF402/3319632507.pdf

http://nitroflare.com/view/AB6D80150A49405/3319632507.epub

Share Button

Anticoagulation Therapy

 Miscellaneous  Comments Off on Anticoagulation Therapy
Apr 262018
 

This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy.
Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.

GET IT FREE HERE

http://nitroflare.com/view/FA18E1BFC930FEE/3319737082.epub

http://nitroflare.com/view/2B78F191FE71EE9/3319737082.pdf

Share Button

Pulmonary Hypertension: Basic Science to Clinical Medicine

 Miscellaneous  Comments Off on Pulmonary Hypertension: Basic Science to Clinical Medicine
Apr 262018
 

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.
GET IT FREE HERE
Share Button

The Bioethics of Regenerative Medicine

 Miscellaneous  Comments Off on The Bioethics of Regenerative Medicine
Apr 262018
 

Regenerative medicine is rich with promethean promises. The use of human embryonic stem cells in research is justified by its advocates in terms of promises to cure a wide range of diseases and disabilities, from Alzheimer’s and Parkinsonism to the results of heart attacks and spinal cord injuries. More broadly, there is the promethean allure of being able to redesign human biological nature in terms of the goals and concerns of humans. Needless to say, these allures and promises have provoked a wide range of not just moral but metaphysical reflections that reveal and reflect deep fault-lines in our cultures.
The essays in this volume, directly and indirectly, present the points of controversy as they tease out the character of the moral issues that confront any attempt to develop the human regenerative technologies that might move us from a human to a post-human nature. Although one can appreciate the disputes as independently philosophical, they are surely also a function of the conflict between a Christian and a post-Christian culture, in that Christianity has from its beginning recognized a fundamental prohibition against the taking of early human life. Even the philosophical disputes that frame secular bioethics are often motivated and shaped by these background cultural conflicts. These essays display this circumstance in rich ways.

GET IT FREE HERE

http://nitroflare.com/view/FC52A816069878B/140208966X.pdf

Share Button

Human Health and Physical Activity During Heat Exposure

 Miscellaneous  Comments Off on Human Health and Physical Activity During Heat Exposure
Apr 232018
 

This book provides fundamental concepts in human thermal physiology and their applications in general public, occupational, military, and athletics settings from the biometeorological perspective. The book includes a section on human physiology, epidemiology and special considerations in aforementioned populations, and behavioral and technological adjustments people may take to combat thermal environmental stress and safeguard their health.
The book is the first of its kind to compile multiple disciplines – human physiology, climatology, and medicine – in one to provide fundamental concepts in human thermal physiology and their applications in general public, occupational, military, and athletics settings from the biometeorological perspective;
Developed by experts, scientists, and physicians from exercise physiology, climatology, public health, sports medicine, and military medicine;
Highlights special considerations and applications of thermal physiology to general public, occupational, military, and athletics settings.
GET IT FREE HERE
Share Button