Antibody Methods and Protocols

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May 112019
 

The rapidly growing field of antibody research is the result of many advancing technologies allowing current developments to take advantage of molecular engineering to create tailor-made antibodies. Antibody Methods and Protocols attempts to provide insight into the generation of antibodies using in vitro and in vivo approaches, as well as technical aspects for screening, analysis, and modification of antibodies and antibody fragments. The detailed volume is focused on basic protocols for isolating antibodies and, at the same time, it selects a range of specific areas with the aim of providing guides for the overall process of antibody isolation and characterization as well as protocols for enhancing classical antibodies and antibody fragments. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and easy to use, Antibody Methods and Protocols provides a broad and useful background to support ongoing efforts by novices and experts alike and encourages the development of new imaginative approaches to this vital area of study.
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Young Children’s Existential Encounters

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May 112019
 

This book is a psychoanalytic observation of five children’s existential encounters in their ordinary life at the nursery. It is among the first within psychosocial literature to go beyond adult experiences and explore the existential in young children’s lives as it plays out in their everydayness in symbolic and sensory articulations and in relationship with others; including with the author as someone who arrived looking for it. The author offers analysis in the form of a writing inquiry into meaning, by means of an on-going movement between the self and the other, the interior and the exterior, and psychoanalytic and existential-phenomenological ideas. This is illustrated through a kaleidoscopic account of May, Nadia, Edward, Baba and Eilidhs’ encounters with nothingness, strangeness, ontological insecurity, death and selfhood as these emerged in the time they spent with the author embodying different forms – from concrete objects to dreams – exemplifying an attunement to existential ubiquity. With its relational ground, this work suggests the potential for adults – including researchers, therapists, trainees, educators and parents – to attune to their own existential encounters as a path to understanding those of children.
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Quirk: Brain Science Makes Sense of Your Peculiar Personality

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May 102019
 

Who are you? It’s the most fundamental of human questions. Are you the type of person who tilts at windmills, or the one who prefers to view them from the comfort of an air-conditioned motorcoach? Our personalities are endlessly fascinating—not just to ourselves but also to our spouses, our parents, our children, our co-workers, our neighbors. As a highly social species, humans have to navigate among an astonishing variety of personalities. But how did all these different permutations come about? And what purpose do they serve? With her trademark wit and sly humor, Hannah Holmes takes readers into the amazing world of personality and modern brain science. Using the Five Factor Model, which slices temperaments into the major factors (Extraversion, Neuroticism, Agreeableness, Conscientiousness, and Openness) and minor facets (such as impulsive, artistic, or cautious), Holmes demonstrates how our genes and brains dictate which factors and facets each of us displays. Are you a Nervous Nelly? Your amygdala is probably calling the shots. Hyperactive Hal? It’s all about the dopamine. Each facet took root deep in the evolution of life on Earth, with Nature allowing enough personal variation to see a species through good times and bad. Just as there are introverted and extroverted people, there are introverted and extroverted mice, and even starfish. In fact, the personality genes we share with mice make them invaluable models for the study of disorders like depression, schizophrenia, and anxiety. Thus it is deep and ancient biases that guide your dealings with a very modern world. Your personality helps to determine the political party you support, the car you drive, the way you eat M&Ms, and the likelihood that you’ll cheat on your spouse. Drawing on data from top research laboratories, the lives of her eccentric friends, the conflicts that plague her own household, and even the habits of her two pet mice, Hannah Holmes summarizes the factors that shape you. And what she proves is that it does take all kinds. Even the most irksome and trying personality you’ve ever encountered contributes to the diversity of our species. And diversity is the key to our survival.
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The Role of Microalgae in Wastewater Treatment

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May 102019
 

This book deals with the most emerging aspects of algal research with special reference to microalgae viz; diversity, mutations, genomics and metagenomics study, eco-physiology, culturing, microalgae for food and feed, biofuel production, harvesting of microalgae, separation, and purification of biochemicals, techno-economical assessment, microalgal biotechnology, algal-bacterial systems for wastewater treatment. It describes the complex issues associated with the above-mentioned areas with the intervention of cutting-edge biotechnological tools and techniques like next-generation sequencing methods, metabolomics, and bioreactor design and development. The chapters provide past developments, current information and future prospects of algal technology as an alternate avenue for waste water treatment and its potential for production of biofuel and nutraceuticals.
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Urban Green Spaces: Public Health and Sustainability in the United States

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May 102019
 

This book crosses disciplinary boundaries to investigate how the benefits of green spaces can be further incorporated in public health. In this regard, the book highlights how ecosystem services provided by green spaces affect multiple aspects of human health and well-being, offering a strategic way to conceptualize the topic.
For centuries, scholars have observed the range of health benefits associated with exposure to nature. As people continue to move to urban areas, it is essential to include green spaces in cities to ensure sustained human health and well-being. Such insights can not only advance the science but also spark interdisciplinary research and help researchers creatively translate their findings into benefits for the public. The book explores this topic in the context of ‘big picture’ frameworks that enhance communication between the environmental, public health, and social sciences.

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Occupational and Environmental Safety and Health

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May 102019
 

This book explores a number of important issues in the area of occupational safety and hygiene. Presenting both research and best practices for the evaluation of occupational risk, safety and health in various types of industry, it particularly focuses on occupational safety in automated environments, innovative management systems and occupational safety in a global context. The different chapters examine the perspectives of all those involved, such as managers, workers and OSH professionals. Based on selected contributions presented at the 15th International Symposium on Occupational Safety and Hygiene (SHO 2019), held on 15–16 April, 2019, in Guimarães, Portugal, the book serves as a timely reference guide and source of inspiration to OSH researchers, practitioners and organizations operating in a global context.
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Deep Learning: Fundamentals, Theory and Applications

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May 092019
 

The purpose of this edited volume is to provide a comprehensive overview on the fundamentals of deep learning, introduce the widely-used learning architectures and algorithms, present its latest theoretical progress, discuss the most popular deep learning platforms and data sets, and describe how many deep learning methodologies have brought great breakthroughs in various applications of text, image, video, speech and audio processing.
Deep learning (DL) has been widely considered as the next generation of machine learning methodology. DL attracts much attention and also achieves great success in pattern recognition, computer vision, data mining, and knowledge discovery due to its great capability in learning high-level abstract features from vast amount of data. This new book will not only attempt to provide a general roadmap or guidance to the current deep learning methodologies, but also present the challenges and envision new perspectives which may lead to further breakthroughs in this field.
This book will serve as a useful reference for senior (undergraduate or graduate) students in computer science, statistics, electrical engineering, as well as others interested in studying or exploring the potential of exploiting deep learning algorithms. It will also be of special interest to researchers in the area of AI, pattern recognition, machine learning and related areas, alongside engineers interested in applying deep learning models in existing or new practical applications.

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Information and Communication Technologies for Ageing Well and e-Health: 4th International Conference, ICT4AWE 2018, Fun

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May 092019
 

This book constitutes the thoroughly refereed proceedings of the third International Conference on Communication Technologies for Ageing Well and e-Health, ICT4AWE 2018, held in Funchal, Madeira, Portugal in March 2018.
The 10 full papers presented were carefully reviewed and selected from 32 submissions. The papers aim at contributing to the understanding of relevant trends of current research on ICT for Ageing Well and eHealth including the ambient assisted living.
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Causality and Development: Neo-Eriksonian Perspectives

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May 082019
 


The third book in Young’s unique trilogy on causality and development continues to locate and define the central role of causality in biopsychosocial and network/systems development, and as a unifying concept of psychology itself. As a way of discussing causality, in general, initially, the book focuses on the acquisition of handedness and hemispheric specialization in infancy and childhood, and their relations to the development of cognition, language, and emotion, in particular. The second part of the book elaborates an innovative 25-step Neo-Eriksonian model of development across the life course based on a Neo-Piagetian model covered in the previous books, completing a step-by-step account of development over the lifespan cognitively and socio-emotionally. It builds on the concept of neo-stage, which is network-based. From this conceptual synthesis, the author’s robust theory of development and causality identifies potential areas for psychological problems and pathology at each developmental step as well as science-based possibilities for their treatment.
This elegant volume:
Presents a clear picture of the development of handedness and laterality in more depth than has been attempted in the literature to date.
Traces the causal concepts of activation-inhibition coordination and networking in the context of development.
Describes in depth a novel 25-step Neo-Eriksonian lifespan model of development.
Reviews relevant research on Piagetian and Eriksonian theories in development.
Emphasizes the clinical utility of the described 25-step Neo-Eriksonian approach to lifespan development.
A significant step in understanding this highly nuanced subject and synthesizing a broad knowledge base, Causality and Development will find an interested audience among developmental psychologists, mental health practitioners, academics, and researchers.chers.

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Essentials of Bioinformatics, Volume I: Understanding Bioinformatics: Genes to Proteins

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May 082019
 

Bioinformatics is an integrative field of computer science, genetics, genomics, proteomics, and statistics, which has undoubtedly revolutionized the study of biology and medicine in past decades. It mainly assists in modeling, predicting and interpreting large multidimensional biological data by utilizing advanced computational methods. Despite its enormous potential, bioinformatics is not widely integrated into the academic curriculum as most life science students and researchers are still not equipped with the necessary knowledge to take advantage of this powerful tool. Hence, the primary purpose of our book is to supplement this unmet need by providing an easily accessible platform for students and researchers starting their career in life sciences. This book aims to avoid sophisticated computational algorithms and programming. Instead, it mostly focuses on simple DIY analysis and interpretation of biological data with personal computers. Our belief is that once the beginners acquire these basic skillsets, they will be able to handle most of the bioinformatics tools for their research work and to better understand their experimental outcomes.

Unlike other bioinformatics books which are mostly theoretical, this book provides practical examples for the readers on state-of-the-art open source tools to solve biological problems. Flow charts of experiments, graphical illustrations, and mock data are included for quick reference. Volume I is therefore an ideal companion for students and early stage professionals wishing to master this blooming field.

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