Microneedles for Transdermal Drug Delivery

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Jul 082019
 

This monograph covers a novel technology to deliver drugs and cosmetics through the skin in a minimally invasive manner. Microneedles – a bed of miniaturized needles is one of the most studied topics in delivering actives through the skin barrier. This book enables readers to understand the delivery of ingredients through the skin, describes a novel and simple method to fabricate microneedles containing a range of small and large molecular weight compounds, studies their physical properties as well as delivery through the skin layers.
Readers will discover this book to be extremely beneficial to help them understand the state of the field of transdermal drug delivery, with extensive coverage including experimental data on basics of microneedle fabrication technology using photolithography, encapsulation of drugs within the polymeric matrix of microneedles and studying their release patternsin vitro and ex vivo .
Academic researchers, pharmaceutical and cosmeceutical industry as well as students of skin science will find this account very useful in their pursuits. As microneedles grow and develop into a commercial reality with more actives being delivered and significant clinical research being put in, this account will hold well in providing basic principles and knowledge together with rigorous experimental data.

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Changing Landscape of Academic Women’s Health Care in the United States

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Jul 082019
 

Since 2005 a dozen states and more than 15 specialties have reported a physician shortage or anticipate one in the next few years. This anticipated shortage and a worsening of physician distribution are compounded by a projected increased demand for women’s healthcare services.Women’s healthcare is particularly vulnerable, because the obstetrician-gynecologist workforce is aging and is among the least satisfied medical specialists. Furthermore, fellowship training in women’s healthcare in internal medicine and in maternal child health in family and community medicine involves only a small portion of general internists and family physicians.In response to this challenge, the Association of American Medical Colleges called for an expansion of medical schools and graduate medical education enrollments. As we cope with significant and rapid changes in organizations and reimbursement, academic departments of obstetrics and gynecology, family and community medicine, and internal medicine have opportunities to create a unified women’s health curriculum for undergraduate students, share preventive health and well-woman expertise in training programs, provide improved continuity of care, instill concepts of lifelong learning to our graduates, and better develop our research programs. This volume’s chapters focus on strategic planning on behalf of academic faculty who will train the anticipated additional load of students, residents, and fellows in women’s healthcare. -changing demographics of faculty -expanding roles of clinician educators -physician investigators and their future -the hidden value of part-time faculty -faculty salaries -required skillsets of academic leaders -the meaning of tenure and faculty satisfaction and retention.Recommendations presented here from authors with distinguished leadership skills indicate a consensus, but not unanimity. In furthering these goals, we summarize in the final chapter our collective expertise and offer ways to implement recommendations to better prepare for tomorrow’s needs in academic women’s healthcare.
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Ecosystems and Human Health: A Critical Approach to Ecohealth Research and Practice

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Jul 072019
 

Ecosystems and Human Health A Critical Approach to Ecohealth Research and Practice Crescentia Dakubo The magnitude of current epidemics, environmental disasters, and extreme weather events is proving that human health problems require more comprehensive solutions than conventional biomedical approaches can offer. At the intersection of the public and community health, global health, and environmental fields, Ecohealth advocates improved health outcomes through better ecosystems management. But even as the Ecohealth approach gains acceptance, literature on the subject is scarce. Ecosystems and Human Health introduces Ecohealth as an emerging field of study, traces its evolution, and explains its applications in cross-disciplinary and holistic programs. Its integrative approach not only focuses on managing the environment to improve health, but also analyzes underlying social and economic determinants of health to develop innovative, people-centered interventions. This unique text: • Expands on the theoretical systems that underlie Ecohealth. • Examines the relationships between human health and the biophysical, political, cultural, and socioeconomic environments. • Discusses the methodological issues and the participatory action research process associated with Ecohealth. • Provides detailed case studies illustrating the approach in developing and developed areas of the world. • Suggests applications of Ecohealth methods to influence public health policy. • Offers practical tools for readers designing and carrying out Ecohealth projects. • Proposes a critical approach to Ecohealth research and practice. Ecohealth holds vital keys to pressing global concerns, giving Ecosystems and Human Health a particular urgency for researchers, students, policymakers, and community and public health practitioners.

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Aeromedical Evacuation: Management of Acute and Stabilized Patients Ed 2

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Jul 072019
 

The definitive treatment on the medical evacuation and management of injured patients in both peace- and wartime. Edited by eminent experts in the field, this text brings together medical specialists from all four branches of the armed services. It discusses the history of aeromedical evacuation, triage and staging of the injured patient, evacuation from site of injury to medical facility, air-frame capabilities, medical capabilities in-flight, response to in-flight emergencies, and mass emergency evacuation. Specific medical conditions are addressed in detail, including such general surgical casualties as abdominal wounds and soft tissue, vascular, maxillofacial, head and spinal cord injuries, ophthalmologic, orthopaedic, pediatric, obstetric-gynecologic casualties, burns, and more. Over 80 illustrations provide a review of transport equipment and both medical and surgical treatment. A must-have reference for all armed forced physicians and flight surgeons, for general and trauma surgeons, internists, intensive care specialists, orthopaedic surgeons, and public health service physicians.
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In Vitro Fertilization: A Textbook of Current and Emerging Methods and Devices Ed 2

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Jul 062019
 

Now in its revised and expanded second edition – including over 20 new chapters – this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world.
With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.

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RNA Processing: Disease and Genome-wide Probing (Advances in Experimental Medicine and Biology)

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Jul 062019
 

Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm.

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Euglena: Biochemistry, Cell and Molecular Biology

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Jul 052019
 

This much-needed book is the first definitive volume on Euglena in twenty-fire years, offering information on its atypical biochemistry, cell and molecular biology, and potential biotechnology applications. This volume gathers together contributions from well-known experts, who in many cases played major roles in elucidating the phenomenon discussed. Presented in three parts, the first section of this comprehensive book describes novel biochemical pathways which in some instances have an atypical subcellular localization. The second section details atypical cellular mechanisms of organelle protein import, organelle nuclear genome interdependence, gene regulation and expression that provides insights into the evolutionary origins of eukaryotic cells. The final section discusses how biotechnologists have capitalized on the novel cellular and biochemical features of Euglena to produce value added products. Euglena: Biochemistry, Cell and Molecular Biology will provide essential reading for cell and molecular biologists with interests in evolution, novel biochemical pathways, organelle biogenesis and algal biotechnology. Readers will come away from this volume with a full understanding of the complexities of the Euglena as well as new realizations regarding the diversity of cellular processes yet to be discovered.

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EMS Supervisor: Principles and Practice

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Jul 052019
 

Emergency medical services (EMS) personnel are thoroughly trained and educated in patient care. They put their knowledge and skills into action at a moment’s notice to treat patients’ illnesses and injuries and to save lives. But what happens when EMS practitioners advance to leadership positions and take on responsibilities beyond patient care? EMS Supervisor: Principles and Practice provides the new or aspiring EMS officer guidance in confronting common challenges faced by those in EMS managerial leadership roles. As an EMS officer, you will be responsible for operations and administration, and the ability to manage and lead will be critically important.

EMS Supervisor: Principles and Practice offers an introduction to creating and maintaining a successful EMS organization through chapters on managerial leadership, team building, professional communications, quality improvement, customer service, strategic planning, crisis management, and budgeting. Establishing knowledge and authority in these areas is crucial to success as an EMS officer.

The concept of five key business priorities (5 BPs), reinforced in each chapter, underlines the primary considerations for EMS officers taking on new responsibilities–people, strategic objectives, financial management objectives, learning objectives, and a culture of quality. Additional features highlight managerial leadership tips, examples of management decisions in the business world outside of EMS, and fictional case studies to stimulate discussion of how EMS officers can resolve challenging situations.

EMS Supervisor: Principles and Practice meets the course outcomes for the National Fire Academy’s Fire and Emergency Services Higher Education (FESHE) Emergency Medical Services Curriculum Management of Emergency Medical Services course.

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Integrating Health Care and Social Services for People with Serious Illness

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Jul 012019
 

by Engineering, and Medicine National Academies of Sciences (Author)

A growing body of research indicates that social determinants of health have a significant impact on health care utilization and outcomes. Researchers and policymakers in the United States have spent decades exploring and discussing approaches to integrating health care and social services. While no nation has a truly integrated system, many other industrialized nations invest more heavily in social services than the United States, and are more effective in integrating these services with health care. Integrating health care and social services, such as accessible housing, meals and nutrition services, transportation, and caregiver training, is particularly important for those facing serious illness who typically encounter multiple chronic conditions, pain and other symptoms, functional dependency, frailty, and significant family caregiver needs.

In an effort to better understand and facilitate discussions about the challenges and opportunities related to integrating health care and social services for people with serious illness, the National Academies of Sciences, Engineering, and Medicine held a full-day public workshop on July 19, 2018 in Washington, DC. The workshop featured a broad range of experts and stakeholders including researchers, policy analysts, patient and family caregiving advocates, and representatives of federal agencies. This publication summarizes the presentations and discussions from the workshop

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Medical Student Survival Skills: History Taking and Communication Skills

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Jun 302019
 


Medical students encounter many challenges on their path to success, from managing their time, applying theory to practice, and passing exams. The Medical Student Survival Skills series helps medical students navigate core subjects of the curriculum, providing accessible, short reference guides for OSCE preparation and hospital placements. These guides are the perfect tool for achieving clinical success.

Medical Student Survival Skills: History Taking and Communication Skills is a concise and compact guide to obtaining and recording medical histories and achieving positive patient interactions. The first section explores taking history—from initial introduction to identifying symptoms—and includes abdominal and chest pain, dizziness and vertigo, shortness of breath, sexual history, confusion and loss of memory. Essential patient communication skills and strategies for various situations are described in the second section, including angry patients, instances of drug and alcohol abuse, diabetes counselling and breaking bad news

About the Author
Philip Jevon is Honorary Clinical Lecturer at Birmingham Medical School and Academy Manager/Tutor, Walsall Teaching Academy, Manor Hospital, Walsall, UK.

Steve Odogwu is Consultant, General Surgery and Senior Academy Tutor, Walsall Teaching Academy, Manor Hospital, Walsall, UK.

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