Traumatic and Ischemic Injury

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Mar 232018
 

This volume focuses on procedures for the development and application of several research animal models and in vitro methods that allow researchers to gain insight into the underlying cellular, biochemical, and physiological mechanisms involved in traumatic and ischemic injury.
The chapters in this book discuss topics, such as animal models and techniques commonly used to study traumatic brain injury, hemorrhagic shock, ischemic and hemorrhagic strokes, sepsis, burn injury, hind limb ischemia, myocardial-ischemia-reperfusion injury, intracranial pressure, global hypoxia-induced perinatal seizures models, and in vitro models. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Traumatic and Ischemic Injury: Methods and Protocols is a valuable resource for novices with limited experience to help them initiate new research projects, and established researchers to help them identify comparable approaches and strategies to their studies in this field.

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The Retinoblastoma Protein

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Mar 232018
 

This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumor suppressor.

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Essential Skills in Family Therapy : From the First Interview to Termination, Third Edition

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Mar 232018
 

Many tens of thousands of students and beginning clinicians have relied on this engaging, authoritative text–now revised and expanded–to hit the ground running in real-world clinical practice. Focusing on what works, the authors show how to flexibly draw on multiple theories and techniques to conduct comprehensive assessments, develop collaborative treatment plans, and intervene effectively for frequently encountered clinical concerns. Mental health skills needed by all therapists are interwoven with state-of-the-art family therapy knowledge. Illustrated with instructive case examples and vignettes, the book helps the reader navigate typical dilemmas and troubleshoot when treatment gets “stuck.”

New to This Edition:

* Discussions of addictive behaviors (pornography, gambling, video games, social media); children’s brain development; premarital counseling; divorce therapy; preventing premature terminations; and uses of technology in clinical practice.
* Chapter on working with older adults and their caregivers.
* Revised throughout with current research and evidence-based practice recommendations.
* Extensively rewritten chapter on treatment planning.
* Chapter-opening vignettes, plus new and revised case examples throughout.
* New assessment resources, including an Appendix on screening instruments.

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http://nitroflare.com/view/83EC10BA2BBDE27/Essential_Skills_in_Family.pdf

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Ruptured Uterus

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Mar 232018
 

The main focus of this book is on ruptured uterus which is a potentially fatal complication during pregnancy. The risk factors and clinical presentation of ruptured uterus vary widely. This book gives an insight into the various possible causes and their presentation. This book aims to sensitize the practicing obstetricians about the need for high level of caution in the deceptive scenarios. The readers would be able to translate the clinical experience and shelf knowledge into every day practice. The cases with similar risks and background will be compiled together under one chapter and at the end of each chapter key points will be highlighted.
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Multiple Myeloma and Other Plasma Cell Neoplasms

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Mar 212018
 

This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration.
Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.

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Chemical Mixtures and Combined Chemical and Nonchemical Stressors: Exposure, Toxicity, Analysis, and Risk

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Mar 212018
 

In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures. This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures.
Additionally, promising tools adapted from other disciplines will be discussed in the context of mixtures toxicology and risk assessment. Finally, the discussion will move beyond chemical mixtures to address incorporating non-chemical stressors into toxicity studies and cumulative risk assessments. Although exposure to multiple chemical and non-chemical stressors is the rule, not the exception, consideration of mixtures in toxicology and risk assessment continues to be a significant challenge. This book will be an essential resource for researchers and professionals in the fields of toxicology, epidemiology, exposure science, risk assessment, and statistics.

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http://nitroflare.com/view/5BC5FB4BEAB5CC0/3319562320.pdf

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Cartilage Regeneration (Stem Cell Biology and Regenerative Medicine)

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Mar 212018
 

This book focuses on cartilage defects and new mesenchymal stem cell-based treatments for their repair and regeneration. Early chapters provide a review of current etiological findings and repair methods of cartilage defects. The next chapters discuss fundamental concepts and features of MSCs, including their proliferation, differentiation, migration and immunomodulatory effects. The discussion also includes clinical applications of MSCs in cartilage tissues, especially with regards to various animal models, biomaterials and transferring techniques. Cartilage Regeneration focuses on the biology of MSCs and their possible applications in cartilage reconstruction, with the goal of bringing new insights into regenerative medicine. It will be essential reading for researchers and clinicians in stem cells, regenerative medicine, biomedical engineering and orthopedic surgery.
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Complex Cases in Total Knee Arthroplasty: A Compendium of Current Techniques

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Mar 212018
 

Covering both primary and revision total knee arthroplasty (TKA), each technique-oriented chapter in this book opens with a clinical case and an overview of the challenges and multiple options for management, and each section within the chapter will describe the physical exam, surgical approach, clinical outcome and recent supporting literature.
Chapters will utilize bullet points for quick reference and plentiful intra-operative photos to illustrate the various techniques described. Part one covers primary TKA, with cases demonstrating management strategies for the varus and valgus knee, flexion contracture, patellofemoral arthritis, and extra-articular deformity, among others, while part two covers revision TKA, with cases demonstrating acute infection, flexion and global instability, severe tibial and femoral bone loss, and periprosthetic fracture, among others.
Written and edited by experts in the field, Complex Cases In Total Knee Arthroplasty: A Collection of Current Techniques will be a useful reference for orthopedic surgeons, residents and fellows as well as sports medicine specialists and anyone involved in surgical care of the knee.

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http://nitroflare.com/view/7E6907898CB8B00/3319693794.pdf

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Handbook of Magnetic Resonance Spectroscopy In Vivo

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Mar 212018
 

This handbook covers the entire field of magnetic resonance spectroscopy (MRS), a unique method that allows the non-invasive identification, quantification and spatial mapping of metabolites in living organisms–including animal models and patients.

Comprised of three parts:

Methodology covers basic MRS theory, methodology for acquiring, quantifying spectra, and spatially localizing spectra, and equipment essentials, as well as vital ancillary issues such as motion suppression and physiological monitoring.
Applications focuses on MRS applications, both in animal models of disease and in human studies of normal physiology and disease, including cancer, neurological disease, cardiac and muscle metabolism, and obesity.
Reference includes useful appendices and look up tables of relative MRS signal-to-noise ratios, typical tissue concentrations, structures of common metabolites, and useful formulae.
About eMagRes Handbooks

eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes Handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry.

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Disease Control Priorities, Third Edition (Volume 7): Injury Prevention and Environmental Health

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Mar 212018
 

The substantial burden of death and disability that results from interpersonal violence, road traffic injuries, unintentional injuries, occupational health risks, air pollution, climate change, and inadequate water and sanitation falls disproportionally on low- and middle-income countries. Injury Prevention and Environmental Health addresses the risk factors and presents updated data on the burden, as well as economic analyses of platforms and packages for delivering cost-effective and feasible interventions in these settings.
The volume’s contributors demonstrate that implementation of a range of prevention strategies-presented in an essential package of interventions and policies-could achieve a convergence in death and disability rates that would avert more than 7.5 million deaths a year.

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http://nitroflare.com/view/960E1CEE035D3FB/1464805229.pdf

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