Molecular Mechanisms of Microbial Evolution

 Microbiology  Comments Off on Molecular Mechanisms of Microbial Evolution
Jan 042019
 

One of the most profound paradigms that have transformed our understanding about life over the last decades was the acknowledgement that microorganisms play a central role in shaping the past and present environments on Earth and the nature of all life forms. Each organism is the product of its history and all extant life traces back to common ancestors, which were microorganisms.
Nowadays, microorganisms represent the vast majority of biodiversity on Earth and have survived nearly 4 billion years of evolutionary change. Microbial evolution occurred and continues to take place in a great variety of environmental conditions. However, we still know little about the processes of evolution as applied to microorganisms and microbial populations. In addition, the molecular mechanisms by which microorganisms communicate/interact with each other and with multicellular organisms remains poorly understood. Such patterns of microbe-host interaction are essential to understand the evolution of microbial symbiosis and pathogenesis.Recent advances in DNA sequencing, high-throughput technologies, and genetic manipulation systems have enabled studies that directly characterize the molecular and genomic bases of evolution, producing data that are making us change our view of the microbial world. The notion that mutations in the coding regions of genomes are, in combination with selective forces, the main contributors to biodiversity needs to be re-examined as evidence accumulates, indicating that many non-coding regions that contain regulatory signals show a high rate of variation even among closely related organisms. Comparative analyses of an increasing number of closely related microbial genomes have yielded exciting insight into the sources of microbial genome variability with respect to gene content, gene order and evolution of genes with unknown functions. Furthermore, laboratory studies (i.e. experimental microbial evolution) are providing fundamental biological insight through direct observation of the evolution process. They not only enable testing evolutionary theory and principles, but also have applications to metabolic engineering and human health. Overall, these studies ranging from viruses to Bacteria to microbial Eukaryotes are illuminating the mechanisms of evolution at a resolution that Darwin, Delbruck and Dobzhansky could barely have imagined. Consequently, it is timely to review and highlight the progress so far as well as discuss what remains unknown and requires future research. This book explores the current state of knowledge on the molecular mechanisms of microbial evolution with a collection of papers written by authors who are leading experts in the field.

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Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets

 Endocrinology/Metabolism/Diabetes Mellitus, Microbiology  Comments Off on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets
Dec 292018
 

The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

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Therapeutic Microbiology: Probiotics and Related Strategies

 Microbiology  Comments Off on Therapeutic Microbiology: Probiotics and Related Strategies
Nov 192018
 

Breaks new ground in explaining the breakthroughs possible with therapeutic microbiology.

Explores the potential and actual uses of the many methods for altering the microbiotas of humans and animals: probiotics, prebiotics, synbiotics, bacteriophages, and replacement therapy.
Describes the biological principles underlying the manipulation of the indigenous microbiota and the biology of the effector organisms that have been utilized for this purpose.
Discusses the many microbes that can potentially be used therapeutically and prophylactically.
Serves as a reference to medical, dental and veterinary practitioners with an interest in alternative approaches to the prevention and treatment of microbial diseases.

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Advances in Microbiology, Infectious Diseases and Public Health: Volume 9

 Infectious Diseases, Microbiology  Comments Off on Advances in Microbiology, Infectious Diseases and Public Health: Volume 9
Nov 082018
 

This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention.
Advances in Microbiology, Infectious Diseases and Public Health is a subseries of Advances in Experimental Medicine and Biology, which has been publishing significant contributions in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. 2016 Impact Factor: 1.881.

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Microbiology: A Laboratory Manual, Global Edition (11th edition – March 30, 2017 Release)

 Microbiology  Comments Off on Microbiology: A Laboratory Manual, Global Edition (11th edition – March 30, 2017 Release)
Oct 202018
 

Easy to adapt for almost any microbiology lab course, this versatile, comprehensive, and clearly written manual is competitively priced and can be paired with any undergraduate microbiology text. Known for its thorough coverage, straightforward procedures, and minimal equipment requirements, the Eleventh Edition incorporates current safety protocols from governing bodies such as the EPA, ASM, and AOAC. The new edition also includes alternate organisms for experiments for easy customization in Biosafety Level 1 and 2 labs. New lab exercises have been added on Food Safety and revised experiments, and include options for alternate media, making the experiments affordable and accessible to all lab programs. Ample introductory material, engaging clinical applications, and laboratory safety instructions are provided for each experiment along with easy-to-follow procedures and flexible lab reports with review and critical thinking questions.

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Medical Microbiology for the New Curriculum: A Case-Based Approach

 Microbiology  Comments Off on Medical Microbiology for the New Curriculum: A Case-Based Approach
Oct 102018
 

Encompassing twenty-four clinically important and frequently encountered infectious diseases, the text provides all the necessary background and the most up-to-date treatment of the microbes that cause diseases in humans. Each fully illustrated case study is introduced with a patient history, differential diagnosis, clinical clues, laboratory data, pathogenesis, treatment, and prevention. Presented as unknowns, the cases challenge readers to create a differential diagnosis just as they would in practice, including noninfectious causes that could present similar clinical findings.

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Oxford Handbook of Infectious Diseases and Microbiology

 Infectious Diseases, Microbiology  Comments Off on Oxford Handbook of Infectious Diseases and Microbiology
Sep 282018
 

 

Fully reviewed and revised for its second edition, the Oxford Handbook of Infectious Diseases and Microbiology maintains its position as the must-have guide to all aspects of infectious diseases and microbiology. Reflecting the current approach to joint postgraduate training programmes, the handbook takes an integrated approach to both subjects. It covers the basic principles of bacteriology and virology, along with specific guidance on individual diseases and conditions, all in the accessible Oxford Handbook style. Now including new topics on important subjects such as microbiology specimen collection, commonly used media, molecular diagnostics, and antimicrobials in pregnancy, as well as incorporating new guidelines from WHO, NICE, and BASHH among others, this handbook ensures that the informaiton you need is accessible, clear, and easy-to-understand.Practical and comprehensive, this handbook includes coverage of National Frameworks and current legislation, together with information on topical issues such as bioterrorism and preventative medicine. Fully reviewed by specialist senior readers, and with useful links to up-to-date clinical information and online resources, this is an important addition to the Oxford Handbook Series.
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Review of Medical Microbiology and Immunology, Twelfth Edition

 Immunology, Microbiology  Comments Off on Review of Medical Microbiology and Immunology, Twelfth Edition
Sep 022018
 

The most concise, easy-to-use, and frequently updated review of the medically important aspects microbiology and immunology
Essential for USMLE and medical microbiology course exam preparation, Review of Medical Microbiology, 12e provides a high-yield review of the basic and clinical aspects of bacteriology, virology, mycology, parasitology, and immunology.

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The Short Textbook of Medical Microbiology Including Parasitology, 10th edition

 Microbiology  Comments Off on The Short Textbook of Medical Microbiology Including Parasitology, 10th edition
Aug 262018
 

• Enriched with new information to keep abreast with latest development in medical microbiology, pandemic of swine flu outbreak, biofilms, new methods of sterilization and disinfection, Ogawa medium, latest immunological tests in Mycobacterium tuberculosis, Napah virus, etc.

• Parasitology and entomology especially incorporated.

• Addition of four new chapters, namely Microbiology in the Service of Human Being, Molecular Techniques in Microbiology, Emerging and Re-emerging Microbial Diseases and Hospital and Laboratory Wastes.

• Clinical microbiology and applied microbiology is targeted to all the medical fraternity especially the students of Medicine and Dentistry.

• Presentation of 10th edition enlarged, thoroughly revised and handy text in elegant and colourful form.

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Review of Microbiology and Immunology, 6th edition

 Immunology, Microbiology  Comments Off on Review of Microbiology and Immunology, 6th edition
Aug 212018
 

• The only MCQ book in any subject written by textbook authors.

• Thoroughly revised, updated and fully colored edition.

• All image based microbiology MCQs of 2016 came from this book.

• Facts and concepts have been taken from latest editions of Harrison (19th), Park (23rd), Jawetz (25th), Apurba Sastry’s Essentials of Medical Microbiology, Apurba Sastry’s Essentials of Medical Parasitology and Ananthanarayan (9th edition).

• Latest updates included such as BMW Rule 2016, Zika, H1N1, Ebola virus, Polio eradication, Vaccine-derived PolioVirus (VDPV), MERS CoV, etc.

• Includes questions along with explanatory answers of AIIMS (2000-2016 Nov), PGI (2000-2016 Nov), JIPMER (2009-2016 Nov), All India (2000-2012), DNB (2000-2012) and recent questions from other national level examinations (2013-2016).

• Contains recent MCQs from state entrance exams such as APPG (2000-2016), TNPG (2009-2016), MHPG (2009-2016), West Bengal PG (2012-2016), COMEDK (2013-2016), CMC Vellore 2016 and latest MCQs from other national and state entrances.

• Image-based question bank is strengthened with new images (more than 500 images are included).

• Only MCQs book on Microbiology written by the subject specialty and textbook authors.

• Interactive 2 hours DVD containing Apurba Sastry’s Microbiology Discussion.

• Chapter-wise concise text in a new layout for enabling students to study antegrade manner and important points given in separate boxes.

• Chapter-wise MCQs with detailed explanations given from previous year exams of National and State exams including DNB and NEET pattern questions.

• Hundred percent authentic and correct answers with updated references.

• More emphasis is given to the sections, like Immunology, Parasitology and Mycology.

• Enriched with lots of tables, flowcharts and mnemonics for better recall by the students.

• Useful for interns, students preparing for entrance exams and for second professional students.

• Author online support for clarification of doubts.

• A must-buy book for All India, AIIMS, PGI, JIPMER, DNB FMGE and state entrance exams.

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