Clear-Cutting Disease Control: Capital-Led Deforestation, Public Health Austerity, and Vector-Borne Infection

 Infectious Diseases  Comments Off on Clear-Cutting Disease Control: Capital-Led Deforestation, Public Health Austerity, and Vector-Borne Infection
Mar 232018
 

The vector-borne Zika virus joins avian influenza, Ebola, and yellow fever as recent public health crises threatening pandemicity.
By a combination of stochastic modeling and economic geography, this book proposes two key causes together explain the explosive spread of the worst of the vector-borne outbreaks.

Ecosystems in which such pathogens are largely controlled by environmental stochasticity are being drastically streamlined by both agribusiness-led deforestation and deficits in public health and environmental sanitation.

Consequently, a subset of infections that once burned out relatively quickly in local forests are now propagating across susceptible human populations whose vulnerability to infection is often exacerbated in structurally adjusted cities. The resulting outbreaks are characterized by greater global extent, duration, and momentum.
As infectious diseases in an age of nation states and global health programs cannot, as much of the present modeling literature presumes, be described by interacting populations of host, vector, and pathogen alone, a series of control theory models is also introduced here. These models, useful to researchers and health officials alike, explicitly address interactions between government ministries and the pathogens they aim to control.

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Deadly Companions: How Microbes Shaped our History, New Updated Edition

 Infectious Diseases  Comments Off on Deadly Companions: How Microbes Shaped our History, New Updated Edition
Mar 222018
 

Ever since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other.

Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man, taking an up-to-date look at ancient plagues and epidemics, and identifying key changes in the way humans have lived – such as our move from hunter-gatherer to farmer to city-dweller – which made us vulnerable to microbe attack.

Showing how we live our lives today – with increasing crowding and air travel – puts us once again at risk, Crawford asks whether we might ever conquer microbes completely, or whether we need to take a more microbe-centric view of the world. Among the possible answers, one thing becomes clear: that for generations to come, our deadly companions will continue to shape human history.

Oxford Landmark Science books are ‘must-read’ classics of modern science writing which have crystallized big ideas, and shaped the way we think.

 

 

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Neglected Tropical Diseases – South Asia

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Mar 222018
 

This book covers all aspects of Neglected Tropical Diseases in the region of South Asia. NTDs constitute a significant part of the total disease burden in this geographic area, including soil borne helminth infections, vector borne viral infections, protozoan infections and a few bacterial infections. The current volume covers the most common neglected viral, bacterial and protozoan infections. On top of that, the last part of the volume is dedicated to the management of neglected tropical diseases.

 

 

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Recombinant Antibodies for Infectious Diseases

 Infectious Diseases  Comments Off on Recombinant Antibodies for Infectious Diseases
Mar 202018
 

There are many principles and applications of recombinant antibodies for infectious diseases. The preferred technology associated to recombinant antibody generation is mainly phage display. The adaptation of antibodies for infectious diseases is an area lacking information as most literature is focused on oncology or autoimmunity. This project highlights the power and potential of antibody phage display for infectious diseases. In addition to that, supplementary information regarding technologies associated to antibody generation and engineering in the context of infectious disease will also help to provide greater insight to the potential of recombinant antibodies for infectious diseases.

 

 

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Allergy Prevention and Exacerbation: The Paradox of Microbial Impact on the Immune System

 Infectious Diseases  Comments Off on Allergy Prevention and Exacerbation: The Paradox of Microbial Impact on the Immune System
Mar 202018
 

Allergy is developing into one of the most prevalent diseases affecting individuals in the very early days of life. While the cause of this epidemic is still unclear, it appears that the westernized life style is playing an important role, which includes nutrition, possibly air pollution as well as hygienic conditions. While epidemiologic studies were able to narrow down these factors, basic research discovered novel mechanisms that control the organism´s tolerance against allergens. Particularly interesting is the role of microorganisms that colonize or infect a host and thereby cause damage and immunological activation followed by sensitization or exacerbation of already existing sensitizations. However at the same time microbial activation of the immune system can help to generate a protective immunity that prevents allergen sensitization. The current book is collecting these evidences and connects epidemiologic and clinical mechanistic knowledge. Only the synthesis of this knowledge will help to find solutions to the ongoing allergy epidemic in terms of public health activities, prevention and therapy.

 

 

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HIV/AIDS in China: Beyond the Numbers

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Mar 172018
 

This book presents the history of HIV/AIDS in China, which over the last three decades has been a gripping tale of exclusion and fear, and then, by turns, of involuntary tragedy, cautious experimentation and finally vigorous response.
It discusses the occurrence, development and epidemic studies and also introduces China’s policies and measures to conquer this epidemic, offering readers valuable insights into China’s approach to prevention in this field.

 

 

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Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions, Fourth Edition

 Infectious Diseases  Comments Off on Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions, Fourth Edition
Mar 092018
 

The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”.
This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.

 

 

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Lennette’s Laboratory Diagnosis of Viral Infections, Fourth Edition

 Infectious Diseases  Comments Off on Lennette’s Laboratory Diagnosis of Viral Infections, Fourth Edition
Mar 052018
 

Written from the perspective of the diagnostician, this bestselling book is the definitive text on the laboratory diagnosis of human viral diseases. It contains a wealth of illustrations, tables, and algorithms to enhance your understanding of this ever-evolving field. The book is a ready reference for virologists, microbiologists, epidemiologists, laboratorians, and infections disease specialists, and students.
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Salmonella Enterica

 Infectious Diseases  Comments Off on Salmonella Enterica
Mar 052018
 

The bacterium Salmonella enterica is a serious bacterial pathogen and causative agent of salmonellosis infections on a worldwide scale. Many clinical isolates of S. entericaS. enterica. Following this, the strengths and limitations of the available molecular tools for effective epidemiological assessment of foodborne salmonellae are collected and critically discussed. Such integration would allow accurate identification of both infection source and transmission route that would lead to implementation of effective control measures. Additionally, the role of Salmonella enterica as a possible therapeutic alternative in the fight against cancer. Although Salmonella enterica tumor selectivity remains unclear, pre-clinical and clinical trials have shown its localization in solid, semi-solid and metastatic tumors. The final chapter reviews some mechanisms and recent trends in the spread of multidrug resistant Salmonella enterica. serovar in Nigeria. Antibiotic use both in animal and human medicine and environmental factors, all have a role in the emergence, persistence and spread of resistance.

 

 

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Infectious Diseases, Second Edition

 Infectious Diseases  Comments Off on Infectious Diseases, Second Edition
Mar 042018
 

The second edition of this concise and practical guide describes infections in geographical areas and provides information on disease risk, concomitant infections (such as co-prevalence of HIV and tuberculosis) and emerging bacterial, viral and parasitic infections in a given geographical area of the world.
Geographic approach means that it�s the only book to guide the health care worker towards a diagnosis based on the location of symptoms and travel history by encouraging the question �where have you been?�
New content covering MERS, Ebola, Zika, and infections transmitted during air and maritime travel
Covers the major infectious disease outbreaks framed in their geographic setting such as� H7N9 �bird flu� influenza, H1N1, Ebola, and Zika
Outstanding international editor team with vast experience on various international infectious disease and as journal editors and key leaders in infection surveillance

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