Introduction to Clinical Infectious Diseases: A Problem-Based Approach

 Infectious Diseases  Comments Off on Introduction to Clinical Infectious Diseases: A Problem-Based Approach
Apr 032019
 

Infectious diseases as a specialty suffers from many unique challenges stemming from lower salaries compared to other medical specialties and difficulty keeping the younger demographic within the field. With emerging infections, new diagnostic and research tools, and changing migration patterns, these problems are amplified; infectious disease specialists are in higher demand than ever with fewer and fewer specialists available to support patients and colleagues outside of the field. To meet these increasing challenges, it is vital for the workforce of the future to have the best training possible. This book aims to provide this support.

As trainees, all physicians face clinical infectious disease scenarios on a daily basis. They receive basic training in common infections, giving them the tools needed for initial diagnostic studies and empiric treatment. This approach, however, still leaves them struggling with nuances of treating common infections, infections that masquerade as other diseases, rare infection, advanced diagnostics, complicating medical conditions, and a wide range of medical complexities. Important clinical microbiology details and host susceptibility risks will be highlighted when discussing uncommon infections.

Each chapter begins by defining a distinct clinical infectious disease problem and the most common cause(s). The next section of each chapter identifies the key questions to consider, including other possible pathogens, medical history, alternate microbiologic diagnoses, instances of unexpected result. This book is the only academic text designed specifically to meet this challenge by targeting learners at all levels. To do this, the text incorporate 30-40 common clinical infectious disease scenarios in both adult and pediatric hosts. It includes easy-to-access “tips and tricks” for when to look further or consider possibilities that are unusual that is useful for someone who is new to the information or has limited experience within infectious diseases. The text heavily features teaching and learning tools, including call out boxes that prioritizes infectious etiologies, host risk factors, important microbiologic clues, and important clinical history clues. The text also includes review questions and quiz-like challenges to reinforce the concepts.

Written by experts in the field Clinical Infectious Diseases is the most cutting-edge academic resource for all medical students, fellows, residents, and trainees, including infectious disease specialists in both adult and pediatric care, internal medicine specialists, and hospitalists.

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Tuberculosis and Superbugs: Examining Tb and Bacterial Infections

 Infectious Diseases  Comments Off on Tuberculosis and Superbugs: Examining Tb and Bacterial Infections
Mar 312019
 

Even though tuberculosis can be successfully treated with antibiotics, it still infects millions of people every year, causing painful, debilitating symptoms and sometimes death. The overuse of antibiotics has lead to the evolution of “superbugs,” creating strains of TB and other diseases that are much more difficult to cure. This book investigates the history of TB and other drug-resistant diseases, explains who is most susceptible, and discusses the very real threat of these diseases today. This book is developed from INVESTIGATING TUBERCULOSIS AND SUPERBUGS: REAL FACTS FOR REAL LIVES to allow republication of the original text into ebook, paperback, and trade editions.

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Modeling to Inform Infectious Disease Control

 Infectious Diseases  Comments Off on Modeling to Inform Infectious Disease Control
Mar 242019
 

Effectively Assess Intervention Options for Controlling Infectious Diseases Our experiences with the human immunodeficiency virus (HIV), severe acute respiratory syndrome (SARS), and Ebola virus disease (EVD) remind us of the continuing need to be vigilant against the emergence of new infectious diseases. Mathematical modeling is increasingly used in the management of infectious disease control as a way to assess interventions relatively quickly, cheaply, and safely. Modeling to Inform Infectious Disease Control shows readers how to take advantage of these models when developing strategies to mitigate infectious disease transmission. The book presents a way of modeling as well as modeling results that help to guide the effective management of infectious disease transmission and outbreak response. It discusses the requirements for preventing epidemics and ways to quantify the impact of preventative public health interventions on the size and dynamics of an epidemic. The book also illustrates how data are used to inform model choice. Accessible to readers with diverse backgrounds, this book explains how to gain insight into the management of infectious diseases through statistical modeling. With end-of-chapter exercises and glossaries of infectious disease terminology and notation, the text is suitable for a graduate-level public health course. Supplementary technical material is provided at the end of each chapter for readers with a stronger background in mathematics and an interest in the art of modeling. In addition, bibliographic notes point readers to literature in which extensions and more general results can be found.

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Urbanization and Slums: Infectious Diseases in the Built Environment

 Infectious Diseases  Comments Off on Urbanization and Slums: Infectious Diseases in the Built Environment
Mar 192019
 

by Engineering, and Medicine National Academies of Sciences (Author), Health and Medicine Division (Author), Board on Global Health (Author), Forum on Microbial Threats (Author), Anna Nicholson (Editor), Cecilia Mundaca Shah (Editor), V. Ayano Ogawa (Editor)

The urban built environment is a prime setting for microbial transmission, because just as cities serve as hubs for migration and international travel, components of the urban built environment serve as hubs that drive the transmission of infectious disease pathogens. The risk of infectious diseases for many people living in slums is further compounded by their poverty and their surrounding physical and social environment, which is often overcrowded, is prone to physical hazards, and lacks adequate or secure housing and basic infrastructure, including water, sanitation, or hygiene services.

To examine the role of the urban built environment in the emergence and reemergence of infectious diseases that affect human health, the National Academies of Sciences, Engineering, and Medicine planned a public workshop. This publication summarizes the presentations and discussions from the workshop

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Prevention and Control of Infections in Hospitals: Practice and Theory

 Infectious Diseases  Comments Off on Prevention and Control of Infections in Hospitals: Practice and Theory
Mar 032019
 

This volume offers extensive information on preventive and infection surveillance procedures, routines and policies adapted to the optimal infection control level needed to tackle today’s microbes in hospital practice. It especially focuses on preventive measures for serious hospital infections. Each chapter includes a practical section that addresses the main aspects of procedures and treatment, and a theoretical section that contains updated documentation that can be used for further study, or to help select infection control measures.

Infection control concerns all healthcare professional working directly or indirectly with patients; in diagnosis, treatment, isolation measures, operations, equipment, drugs, cleaning, textiles, transport, porter service, food and water, building and maintenance, etc.

Hygiene and environmental control is central to infection prevention for patients, visitors and staff alike. Good hygienic practices, individual infection control, well implemented and frequent environmental cleaning, and a high professional standard of hygiene in the treatment and care of patients, are essential to patient safety and a safe working environment. Addressing this essential topic, this book is intended for doctors, nurses and other healthcare workers, students in health-related subjects, hospital managers and health bureaucrats, as well as patients and their families.

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Neuroviral Infections: General Principles and DNA Viruses

 Infectious Diseases, Neurology/Neurosurgery  Comments Off on Neuroviral Infections: General Principles and DNA Viruses
Feb 252019
 


Viral infections of the central nervous system or neurotropic viruses are often lethal. Understanding of these diseases involves understanding the interaction between the nervous system and the immune system. This book provides in-depth information about each individual virus, the diseases they cause, and the mechanisms of spread of those diseases.

Addressing both clinical and basic science aspects, the text covers such diseases as polio, measles, rabies, herpes, West Nile, Japanese encephalitis, and varicella-zoster. The authors also include detailed discussions of molecular pathogenesis and host pathogen immune interaction as well as disease detection, treatment, and prevention.

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Nuclear Medicine in Tropical and Infectious Diseases

 Infectious Diseases, Nuclear Medicine  Comments Off on Nuclear Medicine in Tropical and Infectious Diseases
Feb 152019
 

“More than half of the world’s population is at risk of the tropical diseases malaria, leprosy, schistosomiasis, lymphatic filariasis, onchocerciasis, Chagas’ disease, African trypanosomiasis and leishmaniasis and half a billion are infected with at least one of these diseases”. J. H. F. Remme, World Health Organisation, 1993. “If it is true that science is not limited by frontiers and all research Institutions then belong to mankind, so it is natural for each Institution to be responsible for the problems of those who live in the geographic area under its influence. There are no specific aspects concerning physical, chemical or philosophical concepts and facts, but specificity does exist concerning geology, sociology and pathology. It is the duty of each Institution to study the particular aspects concerning its geographic region, as missing links of the chain of universal knowledge may be found there.” H. L. de Oliveira, fonner Rector of the University ofSiio Paulo, 1967. “Nuclear Medicine is cost effective, especially in the developing countries. ( … ).
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Infectious Complications in Transplant Recipients

 Infectious Diseases  Comments Off on Infectious Complications in Transplant Recipients
Feb 112019
 

Infectious Complications in Transplant Patients has been uniquely designed and formatted to address issues and trends pertaining to pathogens deemed important in critically ill transplant patients. The chapters have been carefully selected so as to direct the focus of the book towards current approaches to controversial, emerging or topical problems in these patients. Each chapter has been authored by a North American and a European specialist. This format serves to impart an added dimension reflective of the diversity of opinions and practices pertaining to unresolved or controversial issues. The authors are recognized experts in their respective fields.
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2019 Nelson’s Pediatric Antimicrobial Therapy (25th Edition) – January 2019 Release

 Infectious Diseases, Pediatrics  Comments Off on 2019 Nelson’s Pediatric Antimicrobial Therapy (25th Edition) – January 2019 Release
Feb 102019
 
This best-selling and widely used resource on pediatric antimicrobial therapy provides instant access to reliable, up-to-the-minute recommendations for treatment of all infectious diseases in children.

For each disease, the authors provide a commentary to help health care providers select the best of all antimicrobial choices. Drug descriptions cover pediatric-appropriate antimicrobials and include complete information about dosing regimens. In response to growing concerns about overuse of antibiotics, the program includes guidelines on when not to prescribe antibiotics.

Now in color to help you find the best options quickly!

New in the 25th edition:

•    Includes recommendations for new intravenous broad-spectrum beta-lactam/beta-lactamase inhibitor combinations.
•    Provides options for treatment of increasing resistance in Escherichia coli for urinary tract infections.
•    Includes updates for management of diarrhea, including recommendations for Giardia with tinidazole and nitazoxanide as drugs of choice, based on the new Infectious Diseases Society of America (IDSA) guidelines.
•    Clarifies specific, new, and evolving recommendations about antifungal therapeutic drug levels for several invasive fungal infections, particularly in immunocompromised children.
•    Reorganizes antiviral table for easier reading: common viral pathogens are in one table and HIV, hepatitis B, and hepatitis C are in a second table.
•    Provides guidance for neonates during the ongoing cefotaxime shortage, including alternatives to achieve similar antibacterial activity in similar tissue sites, with a similar safety profile.
•    Includes updates, such as new information on drug therapy and steroid therapy for neurocysticercosis, incorporating the new IDSA and American Society of Tropical Medicine and Hygiene guidelines.
•    Incorporates new IDSA coccidioidomycosis guidelines in updated recommendations.
•    Simplifies navigation with color-coded tabs and tables that make it easier to find the best treatment options for susceptibility of bacterial, fungal, viral, and parasitic pathogens.

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Fighting Infection in the 21st Century

 Infectious Diseases  Comments Off on Fighting Infection in the 21st Century
Feb 092019
 

The 20th century has seen improvements in both public health and disease prevention which, in turn, have had a dramatic impact on our lives. Success in preventing infection by vaccination and treating infection with antibiotics led some to believe that infectious disease was a thing of the past. However, the adaptability of pathogens and the emergence of new diseases has presented microbiologists with a fresh set of challenges as we enter the new millennium. While celebrating past successes and highlighting developing problems, this volume aims to address some of the issues facing microbiologists in the future. Covering a wide range of topics, it will provide an invaluable resource for microbiologists and an excellent reference for advanced students.Content: Chapter 1 The Global Threat of Emerging Infectious Diseases (pages 1–16): Brian W.J. MahyChapter 2 Can Molecular Techniques be Used in the Prevention of Contamination of Processed Food by Pathogens? (pages 17–36): Thomas J. Humphrey, Gilbert Domingue and Peter H. StephensChapter 3 Is Global Clean Water Attainable? (pages 37–60): Jamie Bartram and Jose HuebChapter 4 Vaccine Development: Past, Present and Future (pages 61–71): Coenraad F.M. HendriksenChapter 5 Live Attenuated Vectors: Have they Delivered? (pages 72–86): Myron M. Levine, James E. Galen, Eileen Barry, Carol Tacket, Karen Kotloff, Oscar Gomez?Duarte, Marcela Pasetti, Thames Pickett and Marcelo SzteinChapter 6 New Malaria Vaccines: The DNA?MVA Prime?Boost Strategy (pages 87–96): Adrian V.S. HillChapter 7 Prospects for New and Rediscovered Therapies: Probiotics and Phage (pages 97–132): Stig BengmarkChapter 8 Vaccine Production in Plants (pages 133–142): Garry C. WhitelamChapter 9 Conserved Epitopes in Bacterial Lipopolysaccharides and Cross?Reactive Antibodies in the Treatment of Endotoxicosis and Gram?Negative Septic Shock (pages 143–178): Sven Muller?Loennies, Franco di Padova, Lore Brade, Didier Heumann and Ernst Theodor RietschelChapter 10 Biological Terrorism (pages 179–182): Paul TaylorChapter 11 Characterization of Bacterial Isolates with Molecular Techniques: Multilocus Sequence Typing (pages 183–197): Martin C.J. MaidenChapter 12 Lessons from the First Antibiotic Era (pages 198–216): Alexander TomaszChapter 13 New Strategies for Identifying and Developing Novel Vaccines: Genome?Based Discoveries (pages 217–236): Ling Lissolo and Marie?Jose Quentin?MilletChapter 14 Are Molecular Methods the Optimum Route to Antimicrobial Drugs? (pages 237–258): Frank C. Odds
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