Immunology of Pregnancy

 Immunology, Ob/Gynae  Comments Off on Immunology of Pregnancy
Mar 052018
 

Reproductive Immunology is a growing area in both immunology and reproductive sciences and is helping us to better understand several complications of pregnancy. Immunology of Pregnancy is the first book to give a complete and up to date review of our knowledge related to the role of the immune system during pregnancy and the interactions between the placenta and the maternal immune system.
This new title covers in detail all the different hypotheses and studies related to the immunology of implantation and provide a practical approach for the application of basic reproductive immunology research to pregnancy complications such as preeclampsia, pre-term labor and IUGR.

 

 

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http://nitroflare.com/view/0B44AA51724B89C/0387306129.pdf

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Staphylococcus aureus: Microbiology, Pathology, Immunology, Therapy and Prophylaxis

 Immunology, Microbiology  Comments Off on Staphylococcus aureus: Microbiology, Pathology, Immunology, Therapy and Prophylaxis
Mar 052018
 

This volume offers a comprehensive overview of basic and applied aspects of Staphylococcus aureus, which is one of the most important human pathogens. It includes sixteen chapters that address the microbiology and immunology of S. aureus, the pathology of its key manifestations, and the current standard of care. Further, it reviews cutting-edge advances in alternative therapeutic and prophylactic approaches to antibiotics.

All chapters were written by respected experts in the field – presenting recent findings on a diverse range of aspects, they are nonetheless interlinked. As such, the book is a must-read for all researchers, clinicians and technicians engaged in basic or applied science work involving S. aureus.

 

 

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http://nitroflare.com/view/36A0E1EAF357B63/3319720619.pdf

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Immunotherapy in Translational Cancer Research

 Immunology, Oncology  Comments Off on Immunotherapy in Translational Cancer Research
Mar 052018
 

A guide to state–of–the–art cancer immunotherapy in translational cancer research

A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer–fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues.

Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world s foremost cancer research and care center and:

Offers a comprehensive presentation of state–of–the–art cancer immunotherapy research that accelerates the pace of clinical cancer care
Filled with the concepts, examples, and approaches for developing individualized therapy
Explores the breath of treatments that reflect the complexity of the immune system itself
Includes contributions from a panel international experts in the field of immunotherapy
Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.

 

 

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http://nitroflare.com/view/11CC00C5022BBC4/1118123220.pdf

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The Immunology of Human Reproduction

 Immunology  Comments Off on The Immunology of Human Reproduction
Mar 042018
 

Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician.

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http://nitroflare.com/view/FA3D2DBA2248B5C/185070791X.pdf

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Oral Mucosa in Health and Disease: A Concise Handbook

 Immunology  Comments Off on Oral Mucosa in Health and Disease: A Concise Handbook
Mar 032018
 

This book is designed to re-establish the position of the oral cavity and its mucosa at the forefront of defence and maintenance of homeostatic mechanisms that protect against disease not just locally but also systemically. The oral mucosa is a unique collection of tissues that constitutes a highly active environment with its own unique microflora and homeostatic interaction with the innate and adaptive immune responses.
As an immune tissue the oral mucosa was somewhat neglected in the past owing to the tendency to assume similarity to the gut mucosa. More recently it has become apparent that the oral mucosa is a complex environment and, like the esophageal mucosa, has more in common with vaginal tissue than with the gut. Furthermore, the ability of the oral mucosa to act as an immune inductive site has made it an attractive area of research in terms of desensitization for allergic reactions and possibly autoimmune responses. In this book, recognized experts in the field provide up-to-date coverage of all aspects of the structure and function of the oral mucosa, reflecting important recent advances in knowledge, including at the molecular level.

 

 

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http://nitroflare.com/view/8B9FC6CC497755C/3319560646.epub

 

http://nitroflare.com/view/4BA78EDE484D1AF/3319560646.pdf

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Immune Infertility

 Immunology  Comments Off on Immune Infertility
Feb 272018
 

Infertility is defned as the inability to conceive after having unprotected intercourse for a year. Infertility is increasing worldwide and has various causes both in the male and the female partner. Immune reactions to sperm can contribute up to 2-30% of infertility.

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http://nitroflare.com/view/009AEF2095D7853/3642013783.pdf

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Regulation of Cytokine Gene Expression in Immunity and Diseases

 Immunology  Comments Off on Regulation of Cytokine Gene Expression in Immunity and Diseases
Feb 142018
 

This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.

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Transanal Endoscopic Microsurgery: Principles and Techniques

 Immunology  Comments Off on Transanal Endoscopic Microsurgery: Principles and Techniques
Feb 132018
 

 

Cancer of the rectum continues to be a significant health problem in industrialized co- tries around the world. Relative 5-year survival rates in the USA for cancer of the rectum from 1995 to 2001 improved to 65%, a 15% improvement over 20 years (American Cancer Society, 2007). The reasons for this dramatic improvement include more accurate pr- perative staging, aggressive neoadjuvant therapy and improved surgical technique as well as specialty-trained surgeons. Despite advances in nonoperative techniques of radiation therapy, chemotherapy and immunotherapy, surgical extirpation continues to be the cornerstone of curative treatment of this potentially lethal disease. Radical cancer excision with total mesorectal excision has become the preferred surgical procedure for even early-stage cancers of the rectum. Over the past decade the enthusiasm for local excision (and other local treatments) has given way to persuasive (predominantly retrospective) evidence that the incidence of locoregional recurrence due to unsuspected lymphatic metastases and positive lateral margins is un- ceptably high even for stage T tumors. Vigorous attempts to find characteristics of the 1 tumor that would allow successful local treatments are ongoing.

 

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http://nitroflare.com/view/2C4D6288A1686BE/Transanal_Endoscopic_Microsurgery.pdf

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Plasma Cell Neoplasms: A Morphologic, Cytogenetic and Immunophenotypic Approach

 Immunology  Comments Off on Plasma Cell Neoplasms: A Morphologic, Cytogenetic and Immunophenotypic Approach
Feb 132018
 

 

This textbook will provide a comprehensive, state-of-the art review the field of diagnostic hematopathology as it’s applied to patients with plasma cell neoplasms. Particular emphasis will be placed on immunophenotypic data – immunohistochemistry and flow cytometry – as well as cytogenetics. We will also discuss how these ancillary data can predict prognosis and chemotherapeutic response. Plasma Cell Neoplasms will serve as a very useful resource for physicians and researchers interested in the plasma cell myeloma diagnosis, therapy, and research. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters will be written by experts in their fields and will include the most up to date scientific and clinical information.

 

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http://nitroflare.com/view/51DC400CC87BB11/3319109170.epub

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Policy Issues in the Clinical Development and Use of Immunotherapy for Cancer Treatment

 Immunology  Comments Off on Policy Issues in the Clinical Development and Use of Immunotherapy for Cancer Treatment
Feb 112018
 

 

Immunotherapy is a form of cancer therapy that harnesses the body’s immune system to destroy cancer cells. In recent years, immunotherapies have been developed for several cancers, including advanced melanoma, lung cancer, and kidney cancer. In some patients with metastatic cancers who have not responded well to other treatments, immunotherapy treatment has resulted in complete and durable responses. Given these promising findings, it is hoped that continued immunotherapy research and development will produce better cancer treatments that improve patient outcomes.

With this promise, however, there is also recognition that the clinical and biological landscape for immunotherapies is novel and not yet well understood. For example, adverse events with immunotherapy treatment are quite different from those experienced with other types of cancer therapy. Similarly, immunotherapy dosing, therapeutic responses, and response time lines are also markedly different from other cancer therapies. To examine these challenges and explore strategies to overcome them, the National Academies of Sciences, Engineering, and Medicine held a workshop in February and March of 2016. This report summarizes the presentations and discussions from the workshop.

 

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http://nitroflare.com/view/637EC280F8619A2/Policy_Issues_in_the_Clinical_Development_and_Use_of_Immunothera.pdf

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