Lippincott Illustrated Reviews: Immunology

 Immunology  Comments Off on Lippincott Illustrated Reviews: Immunology
Aug 112018
 

Publisher’s Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product.
Lippincott’s Illustrated Reviews: Immunology offers a highly visual presentation of essential immunology material, with all the popular features of the series: over 300 full-color annotated illustrations, an outline format, chapter summaries, review questions, and case studies that link basic science to real-life clinical situations. Lippincott’s Illustrated Reviews: Immunology can be used as a review text for a short immunology course, or paired with Lippincott’s Illustrated Reviews: Microbiology for a combined microbiology/immunology course.

 

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Dermatologic Immunity

 Dermatology, Immunology  Comments Off on Dermatologic Immunity
Aug 082018
 

The skin, being the largest organ of the body, is constantly attacked by a diverse array of pathogenic agents including bacteria, viruses and fungi; it also suffers from solar damage and wide fluctuations in temperature and humidity. In some individuals, the immune system, which normally offers protection against fatal external assaults, can malfunction and cause chronic inflammation in the absence of a known pathogen, resulting in a host of disorders categorized as autoimmune skin diseases. This volume contains a series of 19 review articles on a wide range of autoimmune disease processes in the skin. Featuring disorders of humoral as well as cellular immunity, it covers allergic contact dermatitis, toxic epidermal necrolysis, psoriasis, atopic dermatitis, cutaneous lupus erythematosus, bullous pemphigoid, pemphigus foliaceus, lichen planus, vitiligo, scleroderma, alopecia areata and dermatomyositis. For these diseases, the latest insights into their etiology and pathophysiology as well as therapeutic strategies are presented by experts in the fields of dermatology, genetics, immunology and pathology. In addition, overviews of the skin as an active immune organ and of the immune privilege of the skin are included. Comprehensive and up-to-date, this book is recommended for basic and clinical researchers, allergists, immunologists, dermatologists, internists and anyone interested in autoimmunity.

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In Defense of Self: How the Immune System Really Works in Managing Health and Disease

 Immunology  Comments Off on In Defense of Self: How the Immune System Really Works in Managing Health and Disease
Aug 042018
 

We live in a sea of seething microbial predators, an infinity of invisible and invasive microorganisms capable of setting set up shop inside us and sending us to an early grave. The only thing keeping them out? The immune system.
William Clark’s In Defense of Self offers a refreshingly accessible tour of the immune system, putting in layman’s terms essential information that has been for too long the exclusive province of trained specialists. Clark explains how the immune system works by using powerful genetic, chemical, and cellular weapons to protect us from the vast majority of disease-causing microbes-bacteria, viruses, molds, and parasites. Only those microbes our bodies need to help us digest food and process vitamins are admitted. But this same system can endanger us by rejecting potentially life-saving organ transplants, or by overreacting and turning too much force against foreign invaders, causing serious-occasionally lethal-collateral damage to our tissues and organs. Worse yet, our immune systems may react as if we ourselves are foreign and begin snipping away at otherwise healthy tissues, resulting in autoimmune disease. In Defense of Self covers everything from how antibodies work and the strategies the body uses to distinguish self from not self to the nature of immunological memory, the latest approaches to vaccination, and how the immune system will react should we ever be subjected to a bioterrorist attack. Clark also offers important insights on the vital role that the immune system plays in cancer, AIDS, autoimmunity, rheumatoid arthritis, allergies and asthma, and other diseases.
Of special interest to all those suffering from diseases related to the immune system, as well as their families, In Defense of Self lucidly explains a system none of us could live without.

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Between Hope and Fear: A History of Vaccines and Human Immunity

 Immunology  Comments Off on Between Hope and Fear: A History of Vaccines and Human Immunity
Jul 312018
 

A smart and compelling examination of the science of immunity, the public policy implications of vaccine denial, and the real-world outcomes of failing to vaccinate.

If you have a child in school, you may have heard stories of long-dormant diseases suddenly reappearing—cases of measles, mumps, rubella, and whooping cough cropping up everywhere from elementary schools to Ivy League universities because a select group of parents refuse to vaccinate their children.

Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology and disease that has helped eradicate many of the deadliest plagues known to man.

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Clinical Immunology: Principles and Practice – 5th Edition (March 2018 Release)

 Immunology  Comments Off on Clinical Immunology: Principles and Practice – 5th Edition (March 2018 Release)
Jul 282018
 

Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today’s latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice.

User-friendly format features color-coded boxes highlighting critical information on Key Concepts, Clinical Pearls, Clinical Relevance, and Therapeutic Principles.

    • Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response.
    • Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy.

 

    • Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics.

 

    • Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more.

 

    • Summarizes promising research and development anticipated over the next 5-10 years with “On the Horizon” boxes and discussion of translational research.
    • Includes new multiple choice questions in every chapter online, ideal for allergists and rheumatologists seeking certification or recertification in these subspecialties.

 

  • Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

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Complement Activation in Malaria Immunity and Pathogenesis

 Immunology, Pathology  Comments Off on Complement Activation in Malaria Immunity and Pathogenesis
Jul 192018
 

 

Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes.
In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.

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Management of Infections in the Immunocompromised Host

 Immunology  Comments Off on Management of Infections in the Immunocompromised Host
Jul 132018
 

This book provides a comprehensive, state-of-the-art review of the concepts vital to a modern treatment of common and opportunistic infections in the immunocompromised host. Chapters are written by experts in the field, and include their views on gaps in the field and future directions of research. This book begins with an overview of the normally functioning immune system followed by a detailed discussion of the major primary immunodeficiencies. Specific chapters are dedicated to providing practical knowledge in the prevention and treatment of infections in specific immunocompromised patients, including those with cancer, transplant recipients, HIV infection, and autoimmune disorders. Emphasis is placed on diagnostic evaluation, antimicrobial selection that includes consideration of the threat of antimicrobial-resistant pathogens, and immunotherapy tailored to specific patients. Finally, dedicated chapters on stem cell transplantation for patients with primary immunodeficiencies, adoptive cellular immunotherapy, and gene therapy will provide readers with insight into these rapidly evolving and cutting edge therapies.
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Heat Shock Proteins in the Immune System

 Immunology  Comments Off on Heat Shock Proteins in the Immune System
Jun 292018
 

Experts from around the world review the current field of the immunobiology of heat shock proteins, and provide a comprehensive account of how these molecules are spearheading efforts in the understanding of various pathways of the immune system. This one-stop resource contains numerous images to both help illustrate the research on heat shock proteins, and better clarify the field for the non-expert.
Heat shock proteins (HSPs) were discovered in 1962 and were quickly recognized for their role in protecting cells from stress. Twenty years later, the immunogenicity of a select few HSPs was described, and for the past 30 years, these findings have been applied to numerous branches of immunology, including tumor immunology and immunosurveillance, immunotherapy, etiology of autoimmunity, immunotherapy of infectious diseases, and expression of innate receptors. While HSPs can be used to manipulate immune responses by exogenous administration, they appear to be involved in initiation of de novo immune responses to cancer and likely in the maintenance of immune homeostasis.

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Immunopharmacology and Inflammation

 Immunology, Pharmacology  Comments Off on Immunopharmacology and Inflammation
Jun 252018
 

A comprehensive overview of the current research on inflammation and immunopharmacology, with particular attention to the use of anti-inflammatory drugs, this book discusses future trends in this area of pharmacological research. It addresses an audience with basic knowledge in the inflammatory process, immune system and pharmacology. The book meets the needs of graduate students, junior and senior researchers and is useful as a source of the most current information for those already working in these fields.
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Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function

 Immunology  Comments Off on Immunoinformatics: Bioinformatic Strategies for Better Understanding of Immune Function
Jun 152018
 

The astounding diversity of the immune system and the complexity of its regulatory pathways makes immunology a combinatorial science. Computational analysis has therefore become an essential element of immunology research and this has led to the creation of the emerging field of immunoinformatics. This book is the first to feature thorough coverage of this new field.
Immunoinformatics facilitates the understanding of immune function by modelling the interactions among immunological components. Biological research provides ever deeper insights into the complexity of living organisms while computer science provides an effective means to store and analyse large volumes of complex data. Combining the two fields increases the efficiency of biological research and offers the potential for major advances in the study of biological systems.This book encompasses key developments in immunoinformatics, including immunological databases, sequence analysis, structure modelling, mathematical modelling of the immune system, simulation of laboratory experiments, statistical support for immunological experimentation and immunogenomics.

The difficulties in effective application of bioinformatic tools in immunology arise at both ends of the spectrum: most immunologists have only a limited comprehension of sophisticated data analysis and applicability and limitations, while the average computer scientist lacks knowledge of the depth and complexity of biological data. The purpose of this book, therefore, is to present contributions from a multidisciplinary team of biologists and computer scientists to explore the issues related to better understanding of immune function and, in particular, to help apply new computer science methods to immunological research.

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