Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society

 Genetics  Comments Off on Mutating Concepts, Evolving Disciplines: Genetics, Medicine, and Society
Jan 222019
 

Advances in genetics, such as the Human Genome Project’s successful mapping of the human genome and the discovery of ever more sites of disease-related mutations, invite re-examination of basic concepts underlying our fundamental social practices and institutions. Having children, assigning responsibility, identifying causes, using social and scientific resources to improve human well-being, among other concepts, will never be the same. Our concepts of moral and legal responsibility, cause and effect, disease prevention, health, disability, enhancement, personal identity, and reproductive autonomy and responsibility are all subtly changing in response to developments in genetics. Biology, law, medicine, and other disciplines are also evolving in response to mutating concepts in genetics itself-for example, dominance, causation, behavior, gene expression, and gene. The selections in this volume employ philosophical and historical perspectives to shed light on classic social, ethical, and philosophical issues raised with renewed urgency against the backdrop of the mapping of the human genome.
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The Practices of Human Genetics

 Genetics  Comments Off on The Practices of Human Genetics
Jan 152019
 

That concern about human genetics is at the top of many lists of issues requiring intense discussion from scientific, political, social, and ethical points of view is today no surprise. It was in the spirit of attempting to establish the basis for intelligent discussion of the issues involved that a group of us gathered at a meeting of the International Society for the History, Philosophy, and Social Studies of Biology in the Summer of 1995 at Brandeis University and began an exploration of these questions in earlier versions of the papers presented here. Our aim was to cross disciplines and jump national boundaries, to be catholic in the methods and approaches taken, and to bring before readers interested in the emerging issues of human genetics well-reasoned, informative, and provocative papers. The initial conference and elements of the editorial work which have followed were generously supported by the Stifterverband fUr die Deutsche Wissenschaft. We thank Professor Peter Weingart of Bielefeld University for his assistance in gaining this support. As Editors, we thank the anonymous readers who commented upon and critiqued many of the papers and in tum made each paper a more valuable contribution. We also thank the authors for their understanding and patience. Michael Fortnn Everett Mendelsohn Cambridge, MA September 1998 vii INTRODUCTION In 1986, the annual symposium at the venerable Cold Spring Harbor laboratories was devoted to the “Molecular Biology of Homo sapiens.
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Genetics and Genomics for the Cardiologist

 Cardiovascular, Genetics  Comments Off on Genetics and Genomics for the Cardiologist
Jan 132019
 

Genetics and Genomics for the Cardiologist is a concise, but comprehensive volume for the clinical cardiologist or medical student interested in learning how molecular genetics is now being applied to prevention and treatment of heart diseases, from DNA tests to pharmacogenomics and gene-based therapeutics. The volume, written in a plain language, contains detailed figures. A rich glossary, three appendices, many references and several URLs provide additional sources of information.
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Solving Problems in Genetics

 Genetics  Comments Off on Solving Problems in Genetics
Dec 312018
 

The principle objective of this book is to help undergraduate students in the analysis of genetic problems. Many students have a great deal of difficulty doing genetic analysis, and the book will be useful regardless of which genetics text is being used. Most texts provide some kinds of problems and answers: few, if any, however, show the students how to actually solve the problem. Often the student has no idea how the answer was derived. This work emphasizes solutions, not just answers. The strategy is to provide the student with the essential steps and the reasoning involved in conducting the analysis. Throughout the book, an attempt is made to present a balanced account of genetics. Topics, therefore, center about Mendelian, cytogenetic, molecular, quantitative, and population genetics, with a few more specialized areas. Whenever possible the student is provided with the appropriate basic statistics necessary to make some of the analyses. The book also builds on itself; that is, analytical methods learned in early parts of the book are subsequently revisited and used for later analyses. A deliberate attempt is made to make complex concepts simple, and sometimes to point out that apparently simple concepts are sometimes less so on further investigation. Any student taking a genetics course will find this book an invaluable aid to achieving a good understanding of genetic principles and practice.
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DNA Vaccination/Genetic Vaccination

 Genetics  Comments Off on DNA Vaccination/Genetic Vaccination
Dec 312018
 

Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec­ tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene­ delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against both specific infectious diseases and cancers is likely to have dramatic consequences for the develop­ ment of a new generation of experimental vaccines and immune therapies. This technology has the potential to enable the pro­ duction of vaccines and immune-based therapies that are not only effective immunologically but are accessible to the entire world (rather than just to the most developed nations). Vaccine Development Vaccination against pathogenic microorganisms represents one of the most important advances in the history of medicine. Vaccines, including those against polio, measles, mumps, rubella, hepatitis A, hepatitis B, pertussis and other diseases, have dramatically improved and protected more human lives than any other avenue of modern medicine. The vaccine against smallpox, for example, has been so successful that it is now widely believed that this malicious killer, responsible for more deaths in the twentieth century than World Wars I and II combined, has been removed from the face of the earth.
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Genetics: A Ladybird Expert Book (The Ladybird Expert Series)

 Genetics  Comments Off on Genetics: A Ladybird Expert Book (The Ladybird Expert Series)
Dec 192018
 

Who discovered genetics?
How does gene inheritance work?
Is DNA common to all living things?

We inherit CODES from our parents. And these codes are written in the molecule DNA. This DNA means that we RESEMBLE each other, namely our families.

This raises so many questions such as how does DNA influence evolution? How was it discovered? And what does it mean for the future of the human race?

Discover the answers and more inside Adam Rutherford’s Ladybird Expert – Genetics, the thrilling and accessible account that explains race and genetics, whether it is our DNA or the environment that influences us most, what are our chances of being related to royalty, genetic engineering and much more . . .

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http://nitroflare.com/view/D862B2C6EC9196F/Genetics_-_Adam_Rutherford.epub

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USMLE Step 1 Lecture Notes 2018: Biochemistry and Medical Genetics

 Genetics, USMLE  Comments Off on USMLE Step 1 Lecture Notes 2018: Biochemistry and Medical Genetics
Nov 202018
 

Kaplan Medical’s USMLE Step 1 Lecture Notes 2018: Biochemistry and Medical Genetics offers in-depth review with a focus on high-yield topics – a comprehensive approach that will help you deepen your understanding while focusing your efforts where they’ll count the most.
Used by thousands of medical students each year to succeed on USMLE Step 1, Kaplan’s official lecture notes are packed with full-color diagrams and clear review.

The Best Review

Organized in outline format with high-yield summary boxes for efficient study.
Clinical correlations and bridges between disciplines highlighted throughout.
Full-color diagrams and charts for better comprehension and retention.
Updated annually by Kaplan’s all-star expert faculty

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Essentials of Medical Genetics for Nursing and Health Professionals

 Genetics, Nursing  Comments Off on Essentials of Medical Genetics for Nursing and Health Professionals
Nov 182018
 

Essentials of Medical Genetics for Nursing and Other Health Professionals: An Interprofessional Approach is a concise introduction to genetics clinically applicable to nursing students as well as students in other healthcare professions. The text employs an accelerated approach to understanding the fundamentals of genetics, even those with limited knowledge on the topic will find this a beneficial resource. The content is aligned to the ANA’s Essential Genetic and Genomic Competencies and begins with a review of DNE, RNA, protein synthesis, chromosomes, and inheritance patterns. In addition, it takes a clinical focus on specific diseases and groups of disease processes. Each disease chapter focuses on the molecular basis of the disease, the signs and symptoms of the disease, surveillance recommendations, treatment options for the disease, and other disorders. Coverage of diagnostic techniques, embryology and teratogens, diagnostic techniques for genetic testing, prenatal screening, genetics counseling and the ethical, legal, and social issues that surround human genetics and genomics is also included.

Key Features:
Aligned to the ANA’s Essentials of Genetic and Genomic Competencies
Diagnostic techniques for genetic testing
Tables and figures which reinforce comprehension
Interprofessional contributor list across several health specialties

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http://nitroflare.com/view/36E76A9F9F21A78/Essentials_of_Medical_Genetics_for_Nursing_and_Health_Profession.pdf

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Foundations of Perinatal Genetic Counseling

 Genetics, Ob/Gynae  Comments Off on Foundations of Perinatal Genetic Counseling
Nov 132018
 


An essential new text for genetic counseling’s most sought-after skills

Foundations of Perinatal Genetic Counseling is a practical introduction to the concepts and skills in genetic counseling with clients before and during pregnancy. Authored by genetic counselors at the forefront of contemporary perinatal practice, this all-in-one reference provides an accessible yet comprehensive overview of:

· the basics of pregnancy, including assisted reproductive technologies and high-risk pregnancy management
· preimplantation and prenatal genetic screening and diagnosis
· the structure and goals of a genetic counseling appointment
· common clinical scenarios and best-practice approaches

Distilling the most pertinent information for new learners and practicing counselors, Foundations of Perinatal Genetic Counseling is an essential companion for both classroom and clinic. Perinatal genetic counselors will find themselves returning to this unique resource long after their training has come to an end.

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Bioethics, Genetics and Sport

 Genetics  Comments Off on Bioethics, Genetics and Sport
Nov 102018
 

Advances in genetics and related biotechnologies are having a profound effect on sport, raising important ethical questions about the limits and possibilities of the human body. Drawing on real case studies and grounded in rigorous scientific evidence, this book offers an ethical critique of current practices and explores the intersection of genetics, ethics and sport.

Written by two of the world’s leading authorities on the ethics of biotechnology in sport, the book addresses the philosophical implications of the latest scientific developments and technological data. Distinguishing fact from popular myth and science fiction, it covers key topics such as the genetic basis of sport performance and the role of genetic testing in talent identification and development. Its ten chapters discuss current debates surrounding issues such as the shifting relationship between genetics, sports medicine and sports science, gene enhancement, gene transfer technology, doping and disability sport.

The first book to be published on this important subject in more than a decade, this is fascinating reading for anyone with an interest in the ethics of sport, bioethics or sport performance.

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http://nitroflare.com/view/4D390D1826BC3DD/Bioethics%2C_Genetics.pdf

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