Occupational and Environmental Skin Disorders: Epidemiology, Current Knowledge and Perspectives for Novel Therapies

 Dermatology, Epidemiology  Comments Off on Occupational and Environmental Skin Disorders: Epidemiology, Current Knowledge and Perspectives for Novel Therapies
Jun 252018
 

This book provides cutting-edge information on the epidemiology, etiology and pathophysiology of several prevalent occupational and environmental skin diseases (OSD/ESD), with a particular focus on skin health safety issues, risk factors, preventive measures and recent advances in the management of these diseases. It also highlights recent discoveries and developments concerning novel therapeutic agents for inflammatory OSD, especially findings that are supported by clinical data and have the potential to transform conventional prophylactic and therapeutic approaches. For example, despite their increasing prevalence, the management of allergic skin diseases is sometimes challenging, mainly due to limited treatment choices.
In several countries, steroids are the only treatment used. However, in cases of contraindications, adverse effects or unsatisfactory steroidal therapies, alternative treatments are indispensable. As such, an understanding of promising anti-allergic agents enhances allergy research and could eventually lead to novel alternative therapeutic and adjuvant remedies, which are of the utmost importance. This book offers a valuable resource for researchers, graduate students and practitioners in the field of public health in general, especially those working in environmental and occupational medicine, as well as physicians.
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Cancer Epidemiology and Prevention, 4th Edition

 Epidemiology, Oncology  Comments Off on Cancer Epidemiology and Prevention, 4th Edition
Jun 232018
 

Since its initial publication in 1982, Cancer Epidemiology and Prevention has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans.

Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis.

New and timely chapters on environmental and social-epidemiologic factors include:
• The role of social class disparities
• The role of obesity and physical inactivity
• The potential effects of electromagnetic fields and radiofrequency radiation
• The principles of cancer chemoprevention

For both seasoned professionals and newer generations of students and researchers, this fourth edition of Cancer Epidemiology and Prevention remains the authority in the field – a work of distinction that every lab, library, student, professional, or researcher should have close at hand.

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Clinical Epidemiology: The Essentials

 Epidemiology  Comments Off on Clinical Epidemiology: The Essentials
Jun 232018
 

Now in its Fifth Edition, “Clinical Epidemiology: The Essentials” is a comprehensive, concise, and clinically oriented introduction to the subject of epidemiology. Written by expert educators, this text introduces students to the principles of evidence-based medicine that will help them develop and apply methods of clinical observation in order to form accurate conclusions. The Fifth Edition includes more complete coverage of systematic reviews and knowledge management, as well as other key topics such as abnormality, diagnosis, frequency and risk, prognosis, treatment, prevention, chance, studying cases and cause.
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Epidemiology of Sleep: Age, Gender, and Ethnicity

 Epidemiology  Comments Off on Epidemiology of Sleep: Age, Gender, and Ethnicity
Jun 212018
 

What is the prevalence of insomnia in a particular age group, in men and women, or in Caucasians and African Americans? What is the average total sleep time among normal sleepers among these groups? How does the sleep of Caucasians and African Americans differ? These are just some of the questions addressed in The Epidemiology of Sleep.

This new book presents the most detailed and comprehensive archive of normal and abnormal sleep patterns. Based on a landmark study supported by the National Institute on Aging, 772 subjects from a host of populations including men, women, and various age and ethnic groups, prepared detailed sleep diaries for a two-week period. The use of these sleep diaries yielded a plethora of data on such characteristics as normal sleep patterns, various forms of insomnia, fatigue, depression, anxiety, and daytime sleepiness differentiated by age, sex, and ethnicity. The results generated by these data, charted in the book’s numerous tables and graphs, provide a critical methodological advance in the sleep literature.

The Epidemiology of Sleep opens with an overview of the rationale and unique characteristics of the study. This is followed by a comprehensive review of the existing epidemiological literature on sleep. Chapter three presents a detailed description of the methods used in the survey followed by meticulous information on the epidemiology of normal and insomnia sleep, that is unparalleled in the literature. Chapter six provides an archive of sleep patterns among African Americans. The book concludes with a discussion and interpretation of the most interesting findings.

This insightful study, coupled with the comprehensive review of the existing literature on the epidemiology of sleep, make this volume an invaluable resource for sleep researchers, clinicians, health and clinical psychologists, gerontologists, epidemiologists, and advanced students.

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Pain Killer: An Empire of Deceit and the Origin of America’s Opioid Epidemic, 2nd Edition

 Epidemiology  Comments Off on Pain Killer: An Empire of Deceit and the Origin of America’s Opioid Epidemic, 2nd Edition
Jun 132018
 

Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink.

In Pain Killer, Pulitzer Prize–winning New York Times reporter Barry Meier exposes the roots of the most pressing health epidemic of the twenty-first century. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. Purdue turned OxyContin into a billion-dollar blockbuster by launching an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients.

Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. The drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin.

In this updated edition of Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.

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Epidemics and War

 Epidemiology  Comments Off on Epidemics and War
Jun 032018
 

Through its coverage of 19 epidemics associated with a broad range of wars across time and place that blends medical knowledge, demographics, and geographic and medical information with historical and military insights, this book reveals the complex relationship between epidemics and wars throughout history.

• Provides readers with a broad understanding of the relationship between disease and epidemics and their impact upon (and by) wars
• Helps non-medical professionals grasp some of the important elements of specific epidemics―such as disease vectors and common factors assisting diffusion―through explanations in easily understood language
• Blends the perspective from humanistic and social science studies with critical information from science on topics that have continually impacted nations and societies over the ages
• Clarifies the confusing details of similar yet different diseases for readers without medical or scientific backgrounds

About the Author
Rebecca M. Seaman, PhD, is dean of social sciences and humanities at Olympic College in Bremerton, WA.

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Textbook of Epidemiology

 Epidemiology  Comments Off on Textbook of Epidemiology
May 272018
 

Epidemiological research is an important tool for the improvement of preventive and curative healthcare. A valid study design, unbiased study conduct and proper interpretation of study results are essential, as these provide the foundation for evidence-based medicine. This book provides guidance on how to design, conduct and interpret human population-based medical research. It reflects the diversity in the field and will therefore discuss the methodology of etiological, diagnostic, prognostic and intervention research. This textbook is written for bachelor’s and master’s degree students receiving training in the biomedical sciences and for practitioners in the medical and allied professions. It will also serve as a reference manual for those with basic or advanced experience of epidemiology.
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World Epidemics : A Cultural Chronology of Disease From Prehistory to the Era of Zika, Second Edition

 Epidemiology  Comments Off on World Epidemics : A Cultural Chronology of Disease From Prehistory to the Era of Zika, Second Edition
May 092018
 


In its expanded second edition, this chronology examines the effects of epidemic illness and death on human culture from 2700 BCE to 2017. Entries summarize incidents of contagion across the globe, including symptoms, treatment, prevention and demographics, as well as biographical information on notable people who identified and battled disease. Entries feature citations from personal and public documents along with maps, charts comparing types of infection, and estimated populations affected by each epidemic.

“This chronology offers researchers a basic overview of the prevalence of disease during specific historical periods…. Scurvy, black lung, tuberculosis, and unknown contagious infections described in ancient writings receive entries along with better known scourges such as smallpox, plague, and HIV/AIDS.” – Booklist

“this fascinating book is an impressive collection of information that has been finely distilled into a 420-page chronology…the index is invaluable…absorbing…useful glossary…particularly useful to anyone doing preliminary research on a historical disease or epidemic…highly recommended” – Reference Reviews

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Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment

 Epidemiology, Pathology, Physiology  Comments Off on Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment
May 032018
 

A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists.

Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors.

This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.

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Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis

 Epidemiology  Comments Off on Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis
May 012018
 

Two billion people – one-third of the world’s population – are infected with latent tuberculosis. Ten percent of those infected will develop active TB in their lifetimes. A scourge supposedly defeated by antibiotics half a century ago, tuberculosis kills more people today than ever before in history. And the numbers aren’t getting any better. Worse yet this ancient disease is undergoing a metamorphosis, adapting to our misused medications, growing stronger, becoming unbeatable – becoming multi-drug-resistant.

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