Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment

 Epidemiology, Pathology, Physiology  Comments Off on Resistant Hypertension: Epidemiology, Pathophysiology, Diagnosis and Treatment
May 032018
 

A growing number of people suffer from so-called resistant hypertension, that is to say, high blood pressure that does not respond to treatment. This disorder is of great current interest and importance for public health, being a common clinical problem faced by both primary care clinicians and specialists.

Furthermore, as older age and obesity are among the strongest risk factors for uncontrolled hypertension, the incidence of resistant hypertension will likely increase as the population becomes more elderly and heavier. While the prognosis of resistant hypertension is unknown, cardiovascular risk is undoubtedly increased since patients often have a history of long-standing, severe hypertension complicated by multiple other cardiovascular risk factors.

This volume, compiled by a panel of world-renowned experts, offers a comprehensive exploration of resistant hypertension, covering epidemiology, complex diagnostic aspects, and the therapeutic options currently available, with due attention to overall treatment strategies. New therapeutic agents and procedures, such as renal denervation and baroreceptor stimulation, are also described. In addition, the book addresses the economic aspects of resistant hypertension and the role of the different professional figures, from GPs to hypertension specialists, in dealing with it.

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Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis

 Epidemiology  Comments Off on Timebomb:The Global Epidemic of Multi-Drug Resistant Tuberculosis
May 012018
 

Two billion people – one-third of the world’s population – are infected with latent tuberculosis. Ten percent of those infected will develop active TB in their lifetimes. A scourge supposedly defeated by antibiotics half a century ago, tuberculosis kills more people today than ever before in history. And the numbers aren’t getting any better. Worse yet this ancient disease is undergoing a metamorphosis, adapting to our misused medications, growing stronger, becoming unbeatable – becoming multi-drug-resistant.

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Lyme: The First Epidemic of Climate Change

 Epidemiology  Comments Off on Lyme: The First Epidemic of Climate Change
Apr 222018
 

Lyme disease is spreading rapidly around the globe as ticks move into places they could not survive before. The first epidemic to emerge in the era of climate change, the disease infects half a million people in the US and Europe each year, and untold multitudes in Canada, China, Russia, and Australia.

Mary Beth Pfeiffer shows how we have contributed to this growing menace, and how modern medicine has underestimated its danger. She tells the heart-rending stories of families destroyed by a single tick bite, of children disabled, and of one woman’s tragic choice after an exhaustive search for a cure.

Pfeiffer also warns of the emergence of other tick-borne illnesses that make Lyme more difficult to treat and pose their own grave risks. Lyme is an impeccably researched account of an enigmatic disease, making a powerful case for action to fight ticks, heal patients, and recognize humanity’s role in a modern scourge.

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A Brief History of Blood and Lymphatic Vessels

 Epidemiology  Comments Off on A Brief History of Blood and Lymphatic Vessels
Apr 162018
 

This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it´s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.

 

 

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Alzheimer’s Disease Decoded: The History, Present, and Future of Alzheimer’s Disease and Dementia

 Epidemiology  Comments Off on Alzheimer’s Disease Decoded: The History, Present, and Future of Alzheimer’s Disease and Dementia
Apr 122018
 

The book aims to present, educate and inform individuals about Alzheimer’s disease in a comprehensive manner. Its scope ranges from the discovery of the disease, epidemiology and basic biological principles underlying it, to advanced stem cell therapies used in the treatment of Alzheimer’s. It adopts a ‘global’ perspective on Alzheimer’s disease, and include epidemiological data and science from countries around the world.Alzheimer’s disease is a rapidly growing problem seen in every country around the world. This is the first and only comprehensive book to cover Alzheimer’s disease, and includes the most updated literature and scientific progress in the field of dementia and Alzheimer’s disease research.Most books on the market that focus on Alzheimer’s disease are targeted at caregivers as practical advice on how to deal with loved ones with the disease. This book instead is a comprehensive and popular science book that can be read by anyone with an interest in learning more about the disease.Dr. Jefferson Chen MD, PhD, co-author, participated in the world’s first surgical clinical trial using shunts to treat Alzheimer’s disease. His first-hand involvement in a clinical trial for patients with Alzheimer’s disease and experience treating Normal Pressure Hydrocephalus (NPH) which is commonly misdiagnosed as Alzheimer’s disease lends a unique perspective.This book with appeal to a wide audience, regardless of their scientific or educational background.
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Umbrella Reviews!: Evidence Synthesis with Overviews of Reviews and Meta-Epidemiologic Studies

 Epidemiology  Comments Off on Umbrella Reviews!: Evidence Synthesis with Overviews of Reviews and Meta-Epidemiologic Studies
Apr 112018
 

Explains how to read, interpret, and independently conduct umbrella reviews
Written by a multinational team of contributors who provide a multidisciplinary and multidimensional approach
First book to be devoted solely to umbrella reviews

This book is an ideal guide to umbrella reviews, overviews of reviews, and meta-epidemiologic studies for evidence synthesis. Research is conducted at different levels: primary research consists of original studies while secondary research comprises qualitative reviews, systematic reviews, and meta-analyses. Recently, a novel further level of research has been introduced, based on the analysis and pooling of reviews and meta-analysis. This book is the first to focus solely on this new type of research design, which permits a comprehensive and powerful synthesis of scientific evidence in medicine as well as in many other fields in order to inform decision-making. All aspects are covered, including review design and registration, the searching, abstracting, appraisal, and synthesis of evidence, the appraisal of moderators and confounders, and state of the art reporting. Case studies in a range of medical specialties are then presented. The hands-on approach of the book, written by a multinational team of experts, will enable the reader to interpret and independently conduct umbrella reviews.

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Infective Endocarditis: Epidemiology, Diagnosis, Imaging, Therapy, and Prevention

 Epidemiology, Radiology  Comments Off on Infective Endocarditis: Epidemiology, Diagnosis, Imaging, Therapy, and Prevention
Apr 062018
 


This reference resource represents the consensus opinion a team of international specialists on the diagnosis and treatment of infective endocarditis (IE), many of whom have been co-authors of American or European guidelines on the topic. It is therefore a useful tool for many practitioners: cardiologists and cardiac imagers, cardiac surgeons, echocardiographers, specialists of internal medicine, neurologists, and infectiologists.
​​​Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, the mural endocardium, or a septal defect. Its intracardiac effects include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. If left untreated, IE is generally fatal. IE is a changing disease with new diagnostic techniques, new therapeutic strategies, more frequent elderly people and patients with prosthetic valves of intravenous drug users.

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Etiology of Acute Leukemias in Children

 Epidemiology  Comments Off on Etiology of Acute Leukemias in Children
Apr 052018
 

Childhood acute leukemias are one of the main causes of death in children aged 1 to 14 years in some countries; and unfortunately, we have been unable to prevent it. Certainly, a good parcel of it is due to the poor understanding about its etiology. This book aims to describe the most important theories and hypothesis regarding childhood acute leukemia. Written by the most outstanding researchers in the field, this book intends to contribute to a greater understanding of the etiology of this disease. It goes beyond the simple and common analysis of risk factors, which hardly allows us to draw definite conclusions. By addressing the etiology of the disease, discussing from molecular biology until epidemiology and clinical manifestations, this book will guide present and future approaches, contributing for a better clinical management of leukemia in children. The knowledge regarding etiology is a crucial step for a better evaluation, prevention and treatment of a disease. Thus, this book finally intends to provide such knowledge, allowing physicians and practitioners to a better manage of childhood acute leukemias.

 

 

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A Clinician’s Guide to Statistics and Epidemiology in Mental Health: Measuring Truth and Uncertainty

 Epidemiology, Statistics  Comments Off on A Clinician’s Guide to Statistics and Epidemiology in Mental Health: Measuring Truth and Uncertainty
Apr 022018
 

Accessible and clinically relevant, A Clinician’s Guide to Statistics and Epidemiology in Mental Health describes statistical concepts in plain English with minimal mathematical content, making it perfect for the busy health professional. Using clear language in favour of complex terminology, limitations of statistical techniques are emphasized, as well as the importance of interpretation – as opposed to ‘number-crunching’ – in analysis. Uniquely for a text of this kind, there is extensive coverage of causation and the conceptual, philosophical and political factors involved, with forthright discussion of the pharmaceutical industry’s role in psychiatric research. By creating a greater understanding of the world of research, this book empowers health professionals to make their own judgments on which statistics to believe – and why.

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Multidisciplinary Teleconsultation in Developing Countries

 Epidemiology  Comments Off on Multidisciplinary Teleconsultation in Developing Countries
Apr 012018
 

This book presents a replicable model of multidisciplinary teleconsultation, designed and set up by Global Health Telemedicine, that offers very significant health benefits in remote and rural areas of developing countries. The model is based on experiences gained in sub-Saharan Africa while training and cooperating with local health professionals within the DREAM program, managed by the Community of Sant’Egidio. This program has to date treated almost 300,000 patients across many countries and has provided health education and disease prevention training to tens of millions.
It originated in the context of the fight against AIDS but has been extended to encompass other pathologies and to exploit the capabilities of new telemedicine technologies that allow multispecialist teleconsultation (hence the acronym now represents “Disease Relief through Excellent and Advanced Means”). In addition to thorough description of the program, readers will find reflections and analysis on logistical, technical, sociological, and epidemiological issues. The book is divided into thematic chapters with easy-to-understand graphics. It will be a readily accessible source of information for professionals in international cooperation and global health students and professionals.

 

 

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