Endocrine Disorders in Thalassemia: Physiopathological and Therapeutical Aspects

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Endocrine Disorders in Thalassemia: Physiopathological and Therapeutical Aspects
Jan 192019
 

Endocrine glands may be involved in patients with thalassemia major. In the last 20 years, new therapies have significantly improved life expectancy, while several endocrine abnormalities have been described in children, adolescents, and young adults suffering from thalassemia major. The practical objective of this book is to establish guidelines for the management of endocrine disorders underlying the various phases of thalassemic life. Internationally acknowledged experts give a state-of-the-art account of physiopathological and therapeutical approaches to endocrine disorders in thalassemia and focus on such topics as growth hormones, thyroid diseases, puberty, hypogonadism, diabetes, and bone metabolism.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Diabetic Renal-Retinal Syndrome: 21st Century Management Now

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Diabetic Renal-Retinal Syndrome: 21st Century Management Now
Jan 152019
 

After a decade or longer, approximately one-third of individuals with either type 1 or type 2 diabetes commence a downhill course in which decreasing renal function and failing vision define a Renal-Retinal Syndrome, dominating all aspects of life and presaging early death. Only a generation ago, survival after onset of end-stage renal disease (ESRD) in diabetes was limited because rehabilitation was preempted by blindness, limb amputation, stroke, and heart disease. By 1998, however, team management has improved the outlook, with preserved sight and return to work and home responsibilities, usually for a decade or longer, following kidney transplantation and laser photocoagulation. Recognition of the critical requirement for blood pressure regulation and metabolic control are central themes in management. In this unique book, the accomplishments of ophthalmologists, nephrologists, diabetologists, transplant surgeons, and basic scientists are blended into a strategic approach that may be readily applied by all those caring for diabetic patients. Each of twenty-one presentations suitable for primary care physicians, as well as for subspecialists concerned with macrovascular and microvascular complications of diabetes, is placed in perspective by an introductory editorial analysis. Promising near-term innovative therapies, including insertion of genetically engineered beta cells or polymer-coated islets of Langerhans, interdiction of kinins that promote retinal angiogenesis, and prevention of synthesis of advanced glycosylated endproducts (AGEs), are presented in detail. While comprehensive care of diabetic patients reflects multiple incremental advances that in sum afford major benefit, this text envisions further remarkable changes likely to suppress and possibly entirely prevent the Diabetic Renal-Retinal Syndrome.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button
Jan 122019
 

Diabetes is a major public health problem which is expected to affect 160 million people worldwide by the year 2000. Clearly an understanding of the effects of diabetes on the heart is an important step in the development of strategies to reduce the incidence of heart disease for diabetic patients, thus increasing their overall life-expectancy and quality of life. In this book, the editors bring together the different lines of evidence supportive of the idea of a diabetic cardiomyopathy. The first chapter provides an overview of the impact of cardiac dysfunction on the mortality and morbidity of the diabetic population in general, as well as a presentation of clinical aspects of heart disease in diabetes. This is followed by chapters concerned with the pathological and functional changes that occur in the heart as a result of diabetes and a description of the various therapeutic interventions that are available to reverse the effects of diabetes on the heart. Subsequent chapters focus on changes in protein synthesis, membrane function and intermediary metabolism that take place following the onset of diabetes. Since these alterations precede many of the functional and pathological changes, it may be that the processes responsible for the functional decline and tissue injury are initiated by diabetes-induced changes at the cellular and/or biochemical level.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button

Endocrine Hypertension: Underlying Mechanisms and Therapy

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Endocrine Hypertension: Underlying Mechanisms and Therapy
Jan 032019
 

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.

GET IT FREE HERE

http://nitroflare.com/view/E7BDEA5424EF354/1607615479.pdf

ALTERNATIVE LINK

https://filejoker.net/0bo8lmxyrlun

Share Button

Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets

 Endocrinology/Metabolism/Diabetes Mellitus, Microbiology  Comments Off on Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging, and Therapeutic Targets
Dec 292018
 

The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness, cell viability, genomic instability and more. Additional topics include identifying common pathways that are potential candidates for therapeutic intervention, which will stimulate collaboration between groups that are more focused on elucidation of biochemical aspects of stress biology and groups that study the pathophysiological aspects of stress pathways or engaged in drug discovery.

GET IT FREE HERE

http://nitroflare.com/view/A9E18FF117386AC/1461459141_Tumor.pdf

ALTERNATIVE LINK

https://filejoker.net/2unervleusld

Share Button

Nutrition and Type 2 Diabetes: Etiology and Prevention

 Endocrinology/Metabolism/Diabetes Mellitus, Nutrition  Comments Off on Nutrition and Type 2 Diabetes: Etiology and Prevention
Dec 132018
 

Over the past two decades, type 2 diabetes has emerged as a leading threat to global health, and the considerable overlap in obesity and diabetes trends are likely no coincidence.

While the underpinnings for both etiologies are linked to lifestyles, particularly dietary and physical activity patterns, determining optimal approaches for preventing and managing type 2 diabetes using dietary composition remains a challenge. Nutrition and Type 2 Diabetes: Etiology and Prevention rigorously examines various perspectives on diet and type 2 diabetes.

The book presents a comprehensive description and evaluation of the central research to date, primarily in humans, on the macronutrients and their subclasses, micronutrients, foods, beverages, and overall dietary patterns with respect to the risk of type 2 diabetes. It addresses the mediating/mechanistic role of obesity and body composition throughout the text where appropriate. The chapter authors, all leading researchers in the field, discuss fundamental nutritional principles applied to the pathophysiology of type 2 diabetes as well as applied behavioral studies on nutrition and diabetes for each subject area.

The depth and breadth of this book includes aspects of the “food synergy” model for understanding the complicated pathways between nutrition, dietary habits, and risk for type 2 diabetes. It also examines the effects of artificially sweetened beverages and coffee. This reference provides a review of the science on the potential impact of many components of dietary behavior and nutritional properties on etiology and risk for this disease, knowledge that is essential for formulating informed approaches to public health progress in this area.

GET IT FREE HERE

http://nitroflare.com/view/2F1F15C8F5EFBD3/1439850321.pdf

ALTERNATIVE LINK

https://filejoker.net/lhuzf5rckpzi

Share Button

Advanced Exercise Endocrinology

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Advanced Exercise Endocrinology
Nov 112018
 

Advanced Exercise Endocrinology presents a comprehensive examination of the relationship between physical activity and hormone function. As the newest addition to Human Kinetics’ Advanced Exercise Physiology Series, this resource offers the most up-to-date information on the quickly advancing field of exercise endocrinology.

Written by leading exercise endocrinologist Katarina Borer, Advanced Exercise Endocrinology is an essential reference for exercise physiologists, physiotherapists, and other health

GET IT FREE HERE

http://nitroflare.com/view/A91E60734FD4474/073607516X.pdf

ALTERNATIVE LINK

https://filejoker.net/ou534sm7gjgl

Share Button

Frontiers in Gynecological Endocrinology: Volume 3, Ovarian Function and Reproduction – From Needs to Possibilities

 Endocrinology/Metabolism/Diabetes Mellitus, Ob/Gynae, Reproductive Health  Comments Off on Frontiers in Gynecological Endocrinology: Volume 3, Ovarian Function and Reproduction – From Needs to Possibilities
Nov 052018
 

A comprehensive, high-level reference on the ovarian function and and relevant disorders
Provides the latest clinical experience of well-known experts in this continuously evolving field
Offers practical guidance on the evaluation and treatment of female endocrine problems and infertility, and discusses future trends in human reproduction

About this Book
This volume represents an up-to-date overview on ovarian functions and reproduction, providing the reader with the latest advances in gynecological endocrinology. It is published within the International Society of Gynecological Endocrinology (ISGE) Series, and is based on the 2015 International School of Gynecological and Reproductive Endocrinology Winter Course. The book covers a very wide range of topics with particular focus on ovulation and assisted reproduction, ovarian aging and fertility, and premature ovarian failure. The volume will be an invaluable tool for gynecologists, endocrinologists, obstetrician, and experts in women’s health.

GET IT FREE HERE

http://nitroflare.com/view/4D45C94D1640BA1/3319238647.epub

ALTERNATIVE LINK

https://filejoker.net/3xywtgq9765z

Share Button

Type 1 Diabetes: Clinical Management of the Athlete

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Type 1 Diabetes: Clinical Management of the Athlete
Nov 032018
 


There has been a recent surge of new data on the subject of exercise and sport in type I diabetes, as well as great interest from the multidisciplinary healthcare teams looking after such patients. Providing advice and support to enable athletes to manage their diabetes during and after sport is an essential part of diabetes care.

Type I Diabetes: Clinical Management of the Athlete outlines best practice and scientific progress in the management of people with type I diabetes who undertake a sport at any level. The book explores endocrine response to exercise, hypoglycemia and dietetics in the diabetic patient, and provides real-life examples of type I diabetes management at the professional athlete level. It is the first source of reference for specialists in diabetes when seeking advice on how to manage their patient and provides practical advice for equipping the type I diabetes patient with the ability to fulfill their sporting potential.

GET IT FREE HERE

http://nitroflare.com/view/0B50D7AF56A5EC8/0857297538.pdf

ALTERNATIVE LINK

https://filejoker.net/8tpuuwnkctcf

Share Button

Hormones and the Endocrine System: Textbook of Endocrinology

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Hormones and the Endocrine System: Textbook of Endocrinology
Nov 022018
 
This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. But hormones can be found not only in vertebrates, but also in insects, shellfish, spiders, mollusks, even at the origin of metazoan diversification and exhibit the same pathways of synthesis. The book addresses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin. It also discusses the types of hormone receptors, the majority of which are heptahelical G-protein coupled receptors or nuclear receptors. Particular attention is paid to the organs where hormones are created, with specifics on hormonal production and release, while a dedicated chapter details hormonal regulation from very simple to highly complex schemes. The remarkable kinetics of hormones production are also shown, before the book is rounded out by chapters on evolution in the endocrine system, the genetics of endocrine diseases and doping.
GET IT FREE HERE
ALTERNATIVE LINK
Share Button