Handbook of Retinal Screening in Diabetes: Diagnosis and Management

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Handbook of Retinal Screening in Diabetes: Diagnosis and Management
May 162019
 

Beginning with chapters summarizing the basics of diabetic retinopathy, this updated volume outlines the need for screening, how to screen safely and correctly, and the normal condition of the retina without diabetic retinopathy, all using excellent line and halftone illustrations. The core focus then moves on to examining each different form of retinopathy, all supported by outstanding color retinal photographs illustrating the appearance of the retina at various stages of retinopathy, plus an analysis on the best treatment for each stage. The book ends with chapters providing self-assessment questions of the type that screeners will encounter when gaining their now mandatory retinal screening qualifications, as well as a background information chapter offering advice on related UK, European, and US organizations. A website contains all the full-color retinopathy images from the book, with the option to download these into presentations.

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Modelling Metabolism with Mathematica

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May 132019
 

With the advent of sophisticated general programming environments like Mathematica, the task of developing new models of metabolism and visualizing their responses has become accessible to students of biochemistry and the life sciences in general. Modelling Metabolism with Mathematica presents the approaches, methods, tools, and algorithms for modelling the chemical-dynamics of metabolic pathways. The authors explain the concepts underpinning the deterministic theory of chemical and enzyme kinetics, present a graded series of computer models of metabolic pathways leading up to that of the human erythrocyte, and document a consistent set of rate equations and associated kinetic parameters.The experimental and theoretical study of metabolism in mammalian cells has a long and fruitful history, but our understanding of cellular metabolism at the molecular level is far from complete. This book enables its readers to formulate their own models of time-dependent metabolic systems and aids them in the quest for the many fundamental and clinically relevant discoveries that remain to be made.
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JIMD Reports, Volume 43

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on JIMD Reports, Volume 43
May 082019
 

JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
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Prevention of Diabetes

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Prevention of Diabetes
May 052019
 

Expertly authored by the world’s leading specialists in the field, Prevention of Diabetes is the definitive guide for better preventative diabetes care.

Using an evidence-based approach, it outlines the very latest in the identification of people at high risk for type 2 diabetes and how best to use interventional methods such as screening at-risk individuals, pharmaceutical intervention and lifestyle changes.

In addition, it will provide healthcare professionals with the clinical knowledge required to clearly identify the early symptoms of diabetes, enabling them to provide their patients with better clinical care and helping avoid the onset of full-blown diabetes.

Also covered are both the health economics of establishing, and the methods of implement/delivering targeted prevention programmes into clinical and health care practice, based on the vast experience of the editors due to their involvement in such programmes.

Prevention of Diabetes provides clear and expert information in a practical, accessible way, and is ideal reading for all those with an interest in the prevention of diabetes and obesity, such as public health workers, specialists in diabetes and obesity, and GP’s seeing patients with early onset or pre-diabetes symptoms.

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Metabolic and Endocrine Physiology, 3rd Edition

 Endocrinology/Metabolism/Diabetes Mellitus, Physiology  Comments Off on Metabolic and Endocrine Physiology, 3rd Edition
May 042019
 

This book is intended to give readers a “quick look” at metabolic and endocrine physiology. Emphasis is placed on instructional figures, flow diagrams and tables, while text material has been held to a minimum. In general, the endocrine system is first defined and described, and then each endocrine gland is discussed separately.

Where appropriate, common endocrine disorders have also been included. This text concisely elucidates the endocrine mechanisms responsible for maintaining homeostatic control of important physiologic variables, and to assist the reader in understanding common pathophysiologic deviations from normal. Over 360 multiple-choice questions gauge the reader’s capacity to effectively understand the subject material. This new edition contains six new chapters covering: hormone disposition, measurement and secretion; bovine, equine and rodent estrus cycles; primate menstrual cycle; male reproductive system; testosterone, estrogen and progesterone; comparative aspects of endocrinology. Learning objectives have been added at the beginning of each chapter and all of the questions are new.

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Pituitary Disorders of Childhood: Diagnosis and Clinical Management

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Pituitary Disorders of Childhood: Diagnosis and Clinical Management
Apr 292019
 


This unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing’s Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury.

Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary.

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Cardiorespiratory Fitness in Cardiometabolic Diseases: Prevention and Management in Clinical Practice

 Cardiovascular, Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Cardiorespiratory Fitness in Cardiometabolic Diseases: Prevention and Management in Clinical Practice
Apr 232019
 

This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.
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Endothelium: Molecular Aspects of Metabolic Disorders

 Endocrinology/Metabolism/Diabetes Mellitus  Comments Off on Endothelium: Molecular Aspects of Metabolic Disorders
Apr 172019
 


The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual’s life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases.

Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.

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Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology

 Endocrinology/Metabolism/Diabetes Mellitus, Epidemiology, Neurology/Neurosurgery  Comments Off on Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology
Apr 132019
 

This book offers an important reference source about the most common classes of pesticides for researchers engaged in the area of neurotoxicology, metabolism, and epidemiology.
The book presents details about thorough characterization of target and non-target enzymes and proteins involved in toxicity and metabolism; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on an individual country basis as well as on a global basis. The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention.

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The Epidemiology of Diabetes Mellitus: An International Perspective

 Endocrinology/Metabolism/Diabetes Mellitus, Epidemiology  Comments Off on The Epidemiology of Diabetes Mellitus: An International Perspective
Apr 032019
 

This seminal work brings together, for the first time, information on international trends and data for diabetes mellitus. Diabetes is on the increase throughout both the developed and developing world. Currently there are approximately 150 million people with diabetes worldwide, mainly Type 2 diabetes, and it is possible that as many as half of the cases have not been diagnosed. These numbers are likely to increase over the next 25 years. This text takes an international look at the epidemiology of diabetes, focusing primarily on geographical aspects of the disease. Topics covered include:

Etiological factors and time trends Definitions and evidence for prevention Caucasian populations Non-Caucasian populations Associated risk factors and complications Implications The Epidemiology of Diabetes Mellitus: An International Perspective is essential reading for every diabetologist, clinical endocrinologist, epidemiologist and all the members of the diabetes specialist team.

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