Aug 132016
 

The Biochemistry of Retinoid Signaling II: The Physiology of Vitamin A – Uptake, Transport, Metabolism and Signaling (Subcellular Biochemistry)


Features: The Biochemistry of Retinoid Signaling II The Physiology of Vitamin A Uptake Transport Metabolism and Signaling Subcellular Biochemistry

The role of vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes, and the essential details of its mechanism of action have been revealed by investigations carried out by researchers using vertebrate and more recently invertebrate models to study a multiplicity of processes and conditions, encompassing embryogenesis, postnatal development to old age. A wealth of intercellular interactions, intracellular signaling systems, and molecular mechanisms have been described and the overall conclusion is that retinoic acid is essential for life.  This book series, with chapters authored by experts in every aspect of this complex field, unifies the knowledge base and mechanisms currently known in detailed, engaging, well-illustrated, focused chapters that synthesize information for each specific area.
In view of the recent information explosion in this field, it is timely to publish a contemporary, comprehensive, book series recapitulating the most exciting developments in the field and covering fundamental research in molecular mechanisms of vitamin A action, its role in physiology, development, and continued well-being, and the potential of vitamin A derivatives and synthetic mimetics to serve as therapeutic treatments for cancers and other debilitating human diseases.   
Volume II is divided into nine chapters contributed by prominent experts in their respective fields. Each chapter starts with the history of the area of research. Then, the key findings that contributed to development of the field are described, followed by a detailed look at key findings and progress that are being made in current, ongoing research. Each chapter is concluded with a discussion of the relevance of the research and a perspective on missing pieces and lingering gaps that the author recommends will be important in defining future directions in vitamin A research.
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Aug 112016
 

Nanozymes: Next Wave of Artificial Enzymes (SpringerBriefs in Molecular Science)


By (author): Xiaoyu Wang, Wenjing Guo, Yihui Hu, Jiangjiexing Wu, Hui Wei

This book describes the fundamental concepts, the latest developments and the outlook of the field of nanozymes (i.e., the catalytic nanomaterials with enzymatic characteristics). As one of today’s most exciting fields, nanozyme research lies at the interface of chemistry, biology, materials science and nanotechnology. Each of the book’s six chapters explores advances in nanozymes. Following an introduction to the rise of nanozymes research in the course of research on natural enzymes and artificial enzymes in Chapter 1, Chapters 2 through 5 discuss different nanomaterials used to mimic various natural enzymes, from carbon-based and metal-based nanomaterials to metal oxide-based nanomaterials and other nanomaterials. In each of these chapters, the nanomaterials’ enzyme mimetic activities, catalytic mechanisms and key applications are covered. In closing, Chapter 6 addresses the current challenges and outlines further directions for nanozymes. Presenting extensive information on nanozymes and supplemented with a wealth of color illustrations and tables, the book offers an ideal guide for readers from disparate areas, including analytical chemistry, materials science, nanoscience and nanotechnology, biomedical and clinical engineering, environmental science and engineering, green chemistry, and novel catalysis.
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Aug 092016
 

Electrochemical Reduction of Carbon Dioxide: Fundamentals and Technologies (Electrochemical Energy Storage and Conversion)


For Researchers, Students, Industrial Professionals, and Manufacturers

Electrochemical Reduction of Carbon Dioxide: Fundamentals and Technologies is your guide to improved catalytic performance in the electrochemical reduction of carbon dioxide (CO2).Written by electrochemical energy scientists actively involved in environmental research and development, this book addresses the biggest challenge to CO2 electrochemical reduction?low performance of the electrocatalysts?and outlines practical applications for the effective use of CO2. The authorsdiscuss the development of electrochemical energy devices and consider environmental protection on a macroscopic and microscopic scale. Presenting a systematic overview of CO2 electroreduction, they explain the fundamental principles, describe recent advances, and outline applications for future use.

In addition, the authors describe:

  • The main metal electrodes used for CO2 electroreduction
  • Current efficiencies for CO2 reduction products on different metal electrodes
  • The electrochemical conversion of carbon dioxide to produce important chemicals
  • Three categories of reaction conditions: heterogeneous catalysis, low-temperatures electrolysis, and high-temperature electrolysis
  • Developments in CO2 hydrogenation reactions
  • Various analysis methods
  • Progresses in the theoretical electrochemical reduction of CO2

Electrochemical Reduction of Carbon Dioxide: Fundamentals and Technologies covers a variety of topics relevant to the successful use of CO2 electrochemical reduction and utilizes expert contributors at the top of their field. The book functions as a resource for students and professionals involved in materials science, electrochemistry, chemical, energy, electrical, and mechanical engineering.

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Aug 092016
 

Nanofibers of Conjugated Polymers


By (author): A. Sezai Sarac

Conjugated polymer composites with high dielectric constants are being developed by the electronics industry in response to the need for power-grounded decoupling to secure the integrity of high-speed signals and to reduce electromagnetic interference. Electrically conducting polymers are materials that simultaneously possess the physical and chemical properties of organic polymers and the electronic characteristics of metals. Multifunctional micro- and nanostructures of conjugated polymers, such as of pyrrole, have received great attention in recent years because they can polymerize easily and have high conductivity and good thermal stability. They, however, have some disadvantages such as brittleness and hard processability, which can be overcome by developing their nanocomposites. Nanofiber materials with different dielectric properties can be made from conjugated polymer composites and used in the electronics industry, in sensors and batteries, for electrical stimulation to enhance nerve-regeneration process, and for constructing scaffolds for nerve tissue engineering.

Electrospinning is a versatile technique that is used to produce ultrathin continuous fibers with high surface-to-volume and aspect ratios from a variety of materials, including polymers, composites, and ceramics. Conductive materials in fibrillar shape may be advantageous compared with films because of their inherent properties such as anisotropy, high surface area, and mechanical strength. They are of particular interest in electroactive composites as they can be efficiently distributed in an insulating polymer matrix to improve both electrical and mechanical properties. Combination of electrical properties with good mechanical performance is of particular interest in electroactive polymer technology.

This book covers the general aspects of electrospinning and discusses the fundamental concepts that can be used to produce nanofibers with the help of mathematical models and equations. It also details the methods through which different polymeric structures can be included in conjugated polymers during electrospinning to form composites or blends of conjugated polymer nanofibers.

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Jul 162016
 

Progress in the Chemistry of Organic Natural Products 102


The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its “reverse-pharmacology” focus.
The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.

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Jul 162016
 

Ultrafast Biophotonics (Biological and Medical Physics, Biomedical Engineering)


Features: Ultrafast Biophotonics
By (author): P. Vasa, D. Mathur

This book presents emerging contemporary optical techniques of ultrafast science which have opened entirely new vistas for probing biological entities and processes. The spectrum reaches from time-resolved imaging and multiphoton microscopy to cancer therapy and studies of DNA damage. The book displays interdisciplinary research at the interface of physics and biology. Emerging topics on the horizon are also discussed, like the use of squeezed light, frequency combs and terahertz imaging as the possibility of mimicking biological systems. The book is written in a manner to make it readily accessible to researchers, postgraduate biologists, chemists, engineers, and physicists and students of optics, biomedical optics, photonics and biotechnology. 
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Jun 222016
 

Biochemistry and Genetics Pretest Self-Assessment and Review 5/E


Features: Used Book in Good Condition
By (author): Golder N. Wilson M.D.

PreTest is the closest you can get to seeing the USMLE Step 1 before you take it!

500 USMLE-style questions and answers!

Great for course review and the USMLE Step 1, PreTest asks the right questions so you’ll know the right answers. You’ll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest!

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Jun 092016
 

Herbal Medicine in Depression: Traditional Medicine to Innovative Drug Delivery


This book is written for researchers, undergraduate students and postgraduate students, physicians and traditional medicine practitioners who develop research in the field of neurosciences, phytochemistry and ethnopharmacology or can be useful for their practice. Topics discussed include the description of depression, its biochemical causes, the targets of antidepressant drugs, animal and cell models commonly used in the research of this pathology, medicinal plants and bioactive compounds with antidepressant activity used in traditional medicine, advances in nanotechnology for drug delivery to the brain and finally the future challenges for researchers studying this pathology.

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Jun 032016
 

MACPF/CDC Proteins – Agents of Defence, Attack and Invasion (Subcellular Biochemistry)


Features: MACPF CDC Proteins Agents of Defence Attack and Invasion Subcellular Biochemistry

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes.

The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

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May 302016
 

The Retinoids: Biology, Biochemistry, and Disease


By (author): Pascal Dollé, Karen Niederreither

The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. 

The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy.

Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

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