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Plant Reverse Genetics: Methods and Protocols (Methods in Molecular Biology)

 Genetics  Comments Off on Plant Reverse Genetics: Methods and Protocols (Methods in Molecular Biology)
Nov 042019
 

This book describes methods for the analysis of high-throughput genome sequence data, the identification of noncoding RNA from sequence information, the comprehensive analysis of gene expression by microarrays, and metabolomic analysis, all of which are supported by scripts to aid their computational use.
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Applied Statistics in Biomedicine and Clinical Trials Design: Selected Papers from 2013 ICSA/ISBS Joint Statistical Meet

 Statistics  Comments Off on Applied Statistics in Biomedicine and Clinical Trials Design: Selected Papers from 2013 ICSA/ISBS Joint Statistical Meet
Nov 042019
 

This volume is a unique combination of papers that cover critical topics in biostatistics from academic, government, and industry perspectives. The 6 sections cover Bayesian methods in biomedical research; Diagnostic medicine and classification; Innovative Clinical Trials Design; Modelling and Data Analysis; Personalized Medicine; and Statistical Genomics. The real world applications are in clinical trials, diagnostic medicine and genetics. The peer-reviewed contributions were solicited and selected from some 400 presentations at the annual meeting of the International Chinese Statistical Association (ICSA), held with the International Society for Biopharmaceutical Statistics (ISBS). The conference was held in Bethesda in June 2013, and the material has been subsequently edited and expanded to cover the most recent developments.
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Imaging of Male Breast Cancer

 Oncology, Radiology  Comments Off on Imaging of Male Breast Cancer
Nov 032019
 


This book is devoted to the diagnosis and treatment of male breast pathology. It provides a comprehensive overview of current strategies for the diagnosis of breast malignancies in men, with a focus on imaging modalities.

Ultrasound of male breast abnormalities is discussed in particular depth, but the roles of other imaging techniques, genetic tests, and interventional diagnostic modalities are also carefully covered. Special attention is paid to differential diagnosis of malignant and benign lesions, and the most important benign breast diseases are described and illustrated with high-quality images. A special chapter analyzes treatment strategy in men with breast malignancies and principles of follow-up after breast surgery. Individual chapters are also devoted to the diagnosis of recurrent cancer and cancer metastases. This up-to-date and richly illustrated book will interest and assist specialists in ultrasound diagnostics, radiologists, oncologists, and surgeons.

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https://nitroflare.com/view/D64F54377EA11C4/331906049X.pdf

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Resistance to Proteasome Inhibitors in Cancer: Molecular Mechanisms and Strategies to Overcome Resistance

 Oncology  Comments Off on Resistance to Proteasome Inhibitors in Cancer: Molecular Mechanisms and Strategies to Overcome Resistance
Nov 032019
 


The book explores cutting-edge strategies to overcome proteasome inhibitor resistance, including the second generation 20S proteasome inhibitors, novel combinational therapies, and new targets in the ubiquitin-proteasome pathway (e.g., ubiquitin E3 ligases, deubiquitinases, 19S proteasomal ATPases, histone deacetylases, oxidative stress and proteotoxic stress pathways and pharmacogenomic signature profiling) in resistant cancer cells.

The mechanisms of action and resistance of proteasome inhibitors, such as bortezomib and carfilzomib in human cancers, including multiple myeloma, mantle cell lymphoma, acute leukemia, and solid tumors are explored in depth in this volume.

This timely volume unveils the most current discoveries of the mechanisms behind proteasome inhibitor resistance, which will help illuminate the future of cancer therapies.

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Clinical Neurology – 2018

 Neurology/Neurosurgery  Comments Off on Clinical Neurology – 2018
Nov 032019
 

Topics include: evaluation of weakness, neuropathy, myasthenia gravis, demyelinating disease including MS and Guillain-Barre, carpal tunnel, cerebellar disorders, movement disorders (tics, Tourette, dystonia..), tremors, Parkinsons, cerebral palsy, ALS, seizures, strokes, headaches, coma, cervical spine problems, low back pain, radiculopathy, sciatica, myofacial pain, sacroiliac dysfunction, ankylosing spondylitis and pseudo-neurological syndromes.

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The Spectrum of Mineral and Bone Disorder in Chronic Kidney Disease, 2 edition

 Nephrology  Comments Off on The Spectrum of Mineral and Bone Disorder in Chronic Kidney Disease, 2 edition
Nov 032019
 

Despite significant improvement in the management of patients with chronic kidney disease, the morbidity and mortality remain high. However more is now understood about the hormonal influence on bone and vascular structures, and there have been major advances in the field of bone and mineral metabolism. This has lead to the development of new treatment strategies and agents.

This new second edition reflects the most current thinking and understanding in this fascinating field, as presented by world basic and clinical experts.

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https://nitroflare.com/view/D953EA37FDAC5A7/0199559171.pdf

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Managing Prostate Cancer: A Guide for Living Better

 Oncology  Comments Off on Managing Prostate Cancer: A Guide for Living Better
Nov 032019
 

The statistics are sobering: over 200,000 men in the United States are diagnosed with prostate cancer every year. With this diagnosis, men are expected to psychologically combat the worry, practical concerns, and the emotional and physical changes during an immensely trying time. How to help?

In Managing Prostate Cancer: A Guide for Living Better, Dr. Andrew J. Roth, a psychiatrist specializing in psychological support for cancer patients, provides the emotional skills and strategies necessary to help patients deal with the challenges a prostate cancer diagnosis brings to everyday life. These tools, which Dr. Roth terms “Emotional Judo,” effectively teach patients to identify what their fears are rooted in, how to distinguish the rational and irrational aspects of their thoughts and behaviors, make healthier choices to promote a more positive approach, and ultimately transform their lives into a more fulfilling and peaceful journey.

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https://nitroflare.com/view/E5FE47A44BD2022/019933692X.pdf

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Health-related quality of life in cardiovascular patients

 Cardiovascular  Comments Off on Health-related quality of life in cardiovascular patients
Nov 032019
 

A modern definition of health goes beyond the biological dimension to encompass human functionality and well-being. Quality of life is one of the most popular health-related concepts and simultaneously reflects several dimensions of individual health. Health-related quality of life (HRQoL) is taken to include physical, psychological, and social aspects of positive well-being as well as negative effects of illness, treatment, and infirmity. Quality of life outcomes are now considered an important indicator of the success of both diagnostic and therapeutic procedures. In this book, recognized experts discuss the findings of various studies, including their own, regarding HRQoL in patients with cardiovascular diseases. The impact of the newest forms of medical treatment on well-being is considered in patients with arterial hypertension, coronary artery disease, heart failure, arrhythmias, and stroke as well as in patients who have undergone interventional procedures or have implantable cardiac devices. By summarizing established facts and presenting new data, this book will be an invaluable source of information for all practitioners in the field.

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Hepatology: Textbook and Atlas 3rd edition

 Miscellaneous  Comments Off on Hepatology: Textbook and Atlas 3rd edition
Nov 032019
 

Hepatology — a systematic overviewThe 3rd edition has been updated, revised and extended to include some 970 pages. Unique- 530 top-quality coloured figures containing clinical and immunological findings, laparoscopic and and histologic features as well as imaging procedures- all figures directly integrated in the respective text; this results in a new form of learning from “seeing” to “understanding” Attractive- 320 tables in colour- coloured highlighting of important principles and statements for better reading- well-structured and systematic approaches support the content- derived from clinical hepatology for practical use by specialists and in hospital Instructive- detailed presentation of morphology and its integration in liver disease- precise recommendations for therapy and summarized descriptions of special forms of treatment (including a separate chapter on “Therapy”) Manual- about 7,000 references are listed in full; quotations of significant historical publications- first authors of therapy procedures, methods, medical techniques and invasive measures are given as far as possible- comprehensive subject index and register of abbreviationsNEW+ all 530 figures and 320 tables an CD-ROM

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https://nitroflare.com/view/ABA9C551E23B16F/3540768386_Hepatology.pdf

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Toxicologic Pathology for Non-Pathologists

 Pathology, Toxicology  Comments Off on Toxicologic Pathology for Non-Pathologists
Nov 032019
 

This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help non-pathologists understand, contextualize, and communicate the pathology data and interpretations from the study pathologist in a practical and usable format. Within the book, readers will find an overview of general pathology concepts that include fundamental vocabulary and the basics of pathophysiological processes, along with numerous chapters devoted to pathology in specific organ systems as well as topics such as biomarkers, correlation of clinical pathology endpoints (chemistry and hematology) with microscopic changes, and well-known pathology findings for classes of toxic substances.

Authoritative, practical, and comprehensive, Toxicologic Pathology for Non-Pathologists aims to help non-pathologists understand, converse in, and apply a basic understanding of pathology in their day-to-day careers.

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https://nitroflare.com/view/D69AE7863529D67/1493997769.epub

https://nitroflare.com/view/EDB712456B62EDD/1493997769.pdf

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